Evidence map›Paper›PMID 36076994›Full record

ArticleInternational journal of molecular sciences2022

Longterm Increased S100B Enhances Hippocampal Progenitor Cell Proliferation in a Transgenic Mouse Model.

Leticia Rodrigues, Krista Minéia Wartchow, Michael Buchfelder, Diogo Onofre Souza, Carlos-Alberto Gonçalves, Andrea Kleindienst

Open access · goldAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in International journal of molecular sciences, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
0.6field-weighted citation impact, top 36% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed, 7 citations in OpenAlex.

  1. Review
  2. Article
  3. Review
  4. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 2 institutions in 2 countries.

Leticia RodriguesDepartment of Biochemistry, Federal University of Rio Grande do Sul, Porto Alegre 90035003, RS, Brazil.
Krista Minéia WartchowDepartment of Biochemistry, Federal University of Rio Grande do Sul, Porto Alegre 90035003, RS, Brazil.
Michael BuchfelderDepartment of Neurosurgery, Friedrich-Alexander University, 91054 Erlangen, Germany.
Diogo Onofre SouzaDepartment of Biochemistry, Federal University of Rio Grande do Sul, Porto Alegre 90035003, RS, Brazil.
Carlos-Alberto GonçalvesDepartment of Biochemistry, Federal University of Rio Grande do Sul, Porto Alegre 90035003, RS, Brazil.ORCID 0000-0001-8430-5650
Andrea KleindienstDepartment of Neurosurgery, Friedrich-Alexander University, 91054 Erlangen, Germany.ORCID 0000-0003-4758-0324
Universidade Federal do Rio Grande do Sul · BRFriedrich-Alexander-Universität Erlangen-Nürnberg · DE

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

(1) The neurotrophic protein S100B is a marker of brain injury and has been associated with neuroregeneration. In S100Btg mice rendering 12 copies of the murine S100B gene we evaluated whether S100B may serve as a treatment option. (2) In juvenile, adult, and one-year-old S100Btg mice (female and male;

Indexed as

Brain-Derived Neurotrophic FactorHippocampusAnimalsApolipoproteins ECell ProliferationDisease Models, AnimalFemaleMaleMiceMice, TransgenicNeurogenesisS100 Calcium Binding Protein beta SubunitApolipoproteins EBrain-Derived Neurotrophic FactorS100b protein, mouseS100 Calcium Binding Protein beta Subunitadult neurogenesisbrain injuryhippocampusregenerative medicineS100B proteintherapeutic applicationtransgenic animals

Identifiers

PMID36076994
PMCPMC9455494
OpenAlexW4293001314

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.