Evidence map›Paper›PMID 36076917›Full record

ReviewInternational journal of molecular sciences2022

The Neurobiological Links between Stress and Traumatic Brain Injury: A Review of Research to Date.

Lexin Zheng, Qiuyu Pang, Heng Xu, Hanmu Guo, Rong Liu, Tao Wang

Abstract readReview
In one paragraph

Review in International journal of molecular sciences, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed.

  1. Review
  2. Review
  3. Review
  4. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Lexin ZhengDepartment of Forensic Medicine, School of Basic Medicine and Biological Sciences, Soochow University, Suzhou 215123, China.
Qiuyu PangDepartment of Forensic Medicine, School of Basic Medicine and Biological Sciences, Soochow University, Suzhou 215123, China.
Heng XuDepartment of Forensic Medicine, School of Basic Medicine and Biological Sciences, Soochow University, Suzhou 215123, China.
Hanmu GuoDepartment of Forensic Medicine, School of Basic Medicine and Biological Sciences, Soochow University, Suzhou 215123, China.
Rong LiuDepartment of Forensic Medicine, School of Basic Medicine and Biological Sciences, Soochow University, Suzhou 215123, China.
Tao WangDepartment of Forensic Medicine, School of Basic Medicine and Biological Sciences, Soochow University, Suzhou 215123, China.

Funding

a Project Funded by the Priority Academic Program Development of Jiangsu Higher Education Institutions PAPDShanghai Key Lab of Forensic Medicine KF202201Suzhou Municipal Science and Technology Bureau SKJY2021046the National Natural Science Foundation of China 82072110
6 · The paper itself

Abstract

Neurological dysfunctions commonly occur after mild or moderate traumatic brain injury (TBI). Although most TBI patients recover from such a dysfunction in a short period of time, some present with persistent neurological deficits. Stress is a potential factor that is involved in recovery from neurological dysfunction after TBI. However, there has been limited research on the effects and mechanisms of stress on neurological dysfunctions due to TBI. In this review, we first investigate the effects of TBI and stress on neurological dysfunctions and different brain regions, such as the prefrontal cortex, hippocampus, amygdala, and hypothalamus. We then explore the neurobiological links and mechanisms between stress and TBI. Finally, we summarize the findings related to stress biomarkers and probe the possible diagnostic and therapeutic significance of stress combined with mild or moderate TBI.

Indexed as

Brain Injuries, TraumaticBrainHippocampusHumansbiomarkerbrain regionneurological dysfunctionstresstraumatic brain injury

Identifiers

PMID36076917
PMCPMC9455169

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.