ArticleRadiation oncology (London, England)2022
CyberKnife Xsight versus fiducial-based target-tracking: a novel 3D dosimetric comparison in a dynamic phantom.
Article in Radiation oncology (London, England), 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 11 papers.
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11 citing papers in PubMed.
- Segment Anything for Video: A Comprehensive Review of Video Object Segmentation and Tracking from Past to Future.Neurocomputing · 2026Article
- Bridging precision and practice: dual validation of a high-resolution detector array for beam profiling and patient QA in robotic radiosurgery.Physical and engineering sciences in medicine · 2026Article
- Internal target volume reproducibility and dose coverage for lung stereotactic body radiotherapy using spine-based positioning and tracking.Physics and imaging in radiation oncology · 2026Article
- Initial Experience with Correlation Object-Based DRR Targeting Using Stereoscopic X-Ray Imaging in Lung SBRT.Cancers · 2026Article
- A glimpse into the CyberKnife robotic radiosurgery system: technical specifications and developments during thirty years.Frontiers in oncology · 2026Review
- Long-term clinical results of early-stage lung cancer patients treated with risk-adapted stereotactic body radiotherapy using LINAC or CyberKnife : A single-institution analysis of more than 400 cases.Strahlentherapie und Onkologie : Organ der Deutschen Rontgengesellschaft ... [et al] · 2025Article
- Feasibility study of a multi-lesion cyberknife radiotherapy plan verification method using a 2D array with pre-set roll angles.Precision radiation oncology · 2025Article
- Lung metastases.Nature reviews. Disease primers · 2025Review
- Assessing treatment accuracy of image-guided liver stereotactic body radiotherapy: a quantitative analysis based on 4D CT through post-therapeutic MRI-morphologic alterations.Quantitative imaging in medicine and surgery · 2025Article
- Construction and validation of an infant chest phantom for paediatric computed tomography.Physical and engineering sciences in medicine · 2024Article
- A retrospective multi-center feasibility study of a new PTV margin estimation approach for moving targets using CyberKnife log files.Journal of applied clinical medical physics · 2023Article
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Authors and funding
10 authors.
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Abstract
backgroundThe CyberKnife Xsight lung-tracking system (XLTS) provides an alternative to fiducial-based target-tracking systems (FTTS) for non-small-cell lung cancer (NSCLC) patients without invasive fiducial insertion procedures. This study provides a method for 3D independent dosimetric verification of the accuracy of the FTTS compared to the XLTS without relying on log-files generated by the CyberKnife system.
methodsA respiratory motion trace was taken from a 4D-CT of a real lung cancer patient and applied to a modified QUASAR™ respiratory motion phantom. A novel approach to 3D dosimetry was developed using Gafchromic EBT3 film, allowing the 3D dose distribution delivered to the moving phantom to be reconstructed. Treatments were planned using the recommended margins for one and three fiducial markers and XLTS 2-view, 1-view and 0-view target-tracking modalities. The dose delivery accuracy was analysed by comparing the reconstructed dose distributions to the planned dose distributions using gamma index analysis.
resultsFor the 3%/2 mm gamma criterion, gamma passing rates up to 99.37% were observed for the static deliveries. The 3-fiducial and 1-fiducial-based deliveries exhibited passing rates of 93.74% and 97.82%, respectively, in the absence of target rotation. When target rotation was considered, the passing rate for 1-fiducial tracking degraded to 91.24%. The passing rates observed for XLTS 2-view, 1-view and 0-view target-tracking were 92.78%, 96.22% and 76.08%, respectively.
conclusionsExcept for the XLTS 0-view, the dosimetric accuracy of the XLTS was comparable to the FTTS under equivalent treatment conditions. This study gives us further confidence in the CyberKnife XLTS and FTTS systems.
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