Evidence map›Paper›PMID 36076167›Full record

ArticleBMC infectious diseases2022

Different clinical features of children and adults in regional outbreak of Delta COVID-19.

Mei-Zhu Hong, Rongxian Qiu, Wei Chen, Hui Lin, Qing-Qing Xing, Xuan Dong, Jin-Shui Pan, Qin Li

Open access · goldAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in BMC infectious diseases, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
0.3field-weighted citation impact, top 44% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed, 3 citations in OpenAlex.

  1. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 2 institutions in 1 country.

Mei-Zhu Hong *Department of Traditional Chinese Medicine, Mengchao Hepatobiliary Hospital of Fujian Medical University, No. 312, Xihong Road, Fuzhou, 350025, Fujian, China.ORCID http://orcid.org/0000-0002-1042-3838
Rongxian Qiu *Department of Infectious Diseases, Affiliated Hospital of Putian College, Putian, Fujian, China.ORCID http://orcid.org/0000-0003-2479-5664
Wei Chen *Department of Traditional Chinese Medicine, Mengchao Hepatobiliary Hospital of Fujian Medical University, No. 312, Xihong Road, Fuzhou, 350025, Fujian, China.ORCID http://orcid.org/0000-0001-9702-7565
Hui LinDepartment of Traditional Chinese Medicine, Mengchao Hepatobiliary Hospital of Fujian Medical University, No. 312, Xihong Road, Fuzhou, 350025, Fujian, China.ORCID http://orcid.org/0000-0002-8689-5006
Qing-Qing XingDepartment of Hepatology, The First Affiliated Hospital of Fujian Medical University, No. 20, Chazhong Road, Fuzhou, 350005, Fujian, China.ORCID http://orcid.org/0000-0002-7578-014X
Xuan DongDepartment of Hepatology, The First Affiliated Hospital of Fujian Medical University, No. 20, Chazhong Road, Fuzhou, 350005, Fujian, China.ORCID http://orcid.org/0000-0002-5853-2136
Jin-Shui PanDepartment of Hepatology, The First Affiliated Hospital of Fujian Medical University, No. 20, Chazhong Road, Fuzhou, 350005, Fujian, China. j.s.pan76@gmail.com.ORCID http://orcid.org/0000-0002-9586-7760
Qin LiDepartment of Traditional Chinese Medicine, Mengchao Hepatobiliary Hospital of Fujian Medical University, No. 312, Xihong Road, Fuzhou, 350025, Fujian, China. liqing05912006@163.com.ORCID http://orcid.org/0000-0003-4771-6527
Fujian Medical University · CNPutian University · CN

Funding

Emergency Response to COVID-19 of National Administration of Traditional Chinese Medicine 2021ZYLCYJ07-2National Natural Science Foundation of China 81871645Natural Science Foundation of Fujian Province 2020J011218R & D project on the Prevention and Control of COVID-19 from Science and Technology Bureau of Fujian 2021Y0101
6 · The paper itself

Abstract

backgroundThis study compared clinical features of the Delta variant of coronavirus disease 2019 (COVID-19) in children and adults.

methodsClinical data included 80 children and 132 adults with the Delta variant of COVID-19, hospitalized in the Affiliated Hospital of Putian College between September and October 2021. The data was analyzed retrospectively.

resultsThe proportion of mild patients in the children group (50%) was higher than that in the adults group (17.9%). Cough (25%, 20/80) and diarrhea (1.3%, 1/80) symptoms in children group were significantly less frequent. Compared with adults, there was no significant difference in the viral load of SARS-CoV-2 in samples collected by nasopharyngeal swabs. In children, lymphocyte count was higher [1.98 (0.25-4.25) vs 1.20 (0.29-4.27) ×10

conclusionCompared with adults, children with the Delta variant of COVID-19 have differences in symptoms, clinical classification, inflammatory indices, and liver/kidney function injury. Children's illness is relatively mild. Clinicians should pay attention to their differences and use drugs accurately.

Indexed as

COVID-19AdultChildDisease OutbreaksHumansRetrospective StudiesSARS-CoV-2AdultChildClinical chemistryCOVID-19Symptom assessment

Identifiers

PMID36076167
PMCPMC9454403
OpenAlexW4295004882

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.