Evidence map›Paper›PMID 36076123›Full record

Observational studyCanadian journal of anaesthesia = Journal canadien d'anesthesie2022

Changes in sensory block level during a programmed intermittent epidural bolus regimen for labour analgesia: a prospective observational cohort study.

Julia F Casellato, Xiang Y Ye, Kristi Downey, Jose C A Carvalho

Registry-linked trialAbstract readObservational Study
PubMed Publisher
In one paragraph

Observational study in Canadian journal of anaesthesia = Journal canadien d'anesthesie, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT04716660 (Changes in Sensory Block Level During a Programmed Intermittent Epidural Bolus Regimen for Labor Analgesia), which is not on this map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT04716660 completednot on this map

Changes in Sensory Block Level During a Programmed Intermittent Epidural Bolus Regimen for Labor Analgesia: an Observational Cohort Study

TypeobservationalSponsorSamuel Lunenfeld Research Institute, Mount Sinai HospitalRan2021 to 2021Enrolled34ConditionsLabor PainArmsSensory block level check
3 · Its place in the literature

Who cites it

3 citing papers in PubMed.

  1. Trial
  2. Are we closer to determining a gold standard for sensory block testing during labour epidural analgesia?Canadian journal of anaesthesia = Journal canadien d'anesthesie · 2024
    Article
  3. Observational
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Julia F CasellatoDepartment of Anesthesiology and Pain Medicine, Mount Sinai Hospital, University of Toronto, Toronto, ON, Canada. jucasellato@gmail.com.ORCID http://orcid.org/0000-0002-6138-8817
Xiang Y YeMaternal and Infant Care Research Centre, Mount Sinai Hospital, University of Toronto, Toronto, ON, Canada.
Kristi DowneyDepartment of Anesthesiology and Pain Medicine, Mount Sinai Hospital, University of Toronto, Toronto, ON, Canada.
Jose C A CarvalhoDepartment of Anesthesiology and Pain Medicine, Mount Sinai Hospital, University of Toronto, Toronto, ON, Canada.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

purposeIn the context of a programmed intermittent epidural bolus (PIEB) regimen for labour analgesia, one can identify an upper sensory block level (USBL), defined as the highest dermatome with any altered sensation to cold, and a lower sensory block level (LSBL), defined as the highest dermatome with complete sensory block to cold. This study investigated whether and how these sensory block levels vary within PIEB cycles.

methodsWe enrolled patients requesting epidural analgesia. An epidural catheter was placed at L2/L3 or L3/L4. A test dose of 3 mL of bupivacaine 0.125% with fentanyl 3.3 µg·mL

resultsWe studied 30 patients. The USBL and LSBL achieved their peak value 100 min after the loading dose. The median [interquartile range] USBL was T

conclusionOnce peak sensory block levels are established, there is no significant variation in the USBL and LSBL within the PIEB cycles. STUDY REGISTRATION: www. CLINICALTRIALS: gov (NCT04716660); registered 21 January 2021.

Indexed as

Analgesia, EpiduralAnalgesia, ObstetricalAnalgesia, Patient-ControlledAnalgesicsAnesthetics, LocalBupivacaineFentanylHumansProspective StudiesAnalgesicsAnesthetics, LocalBupivacaineFentanylepidural analgesialabour analgesiaobstetric analgesiaprogrammed intermittent epidural bolus (PIEB)sensory block-level testing

Identifiers

What OpenQuestion holds

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Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.