Evidence map›Paper›PMID 36076049›Full record

ArticleInfection2023

Clinically unsuspected orthopedic implants during S. aureus bacteremia do not require additional diagnostic work-up.

Ilse J E Kouijzer, L T D Speijker, E H J G Aarntzen, W H C Rijnen, M P Somford, I Maat, M P A van Meer, J Ten Oever, E H Gisolf

Open access · hybridAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Infection, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
1.7field-weighted citation impact, top 16% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed, 8 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 3 institutions in 1 country.

Ilse J E KouijzerDepartment of Internal Medicine and Radboud Center for Infectious Diseases, Radboud University Medical Center, P.O. Box 9101, 6500 HB, Nijmegen, the Netherlands. Ilse.Kouijzer@radboudumc.nl.
L T D SpeijkerDepartment of Internal Medicine and Radboud Center for Infectious Diseases, Radboud University Medical Center, P.O. Box 9101, 6500 HB, Nijmegen, the Netherlands.
E H J G AarntzenDepartment of Medical Imaging, Radboud University Medical Center, Nijmegen, the Netherlands.
W H C RijnenDepartment of Orthopaedics, Radboud University Medical Center, Nijmegen, the Netherlands.
M P SomfordDepartment of Orthopaedics, Rijnstate Hospital, Arnhem, the Netherlands.
I MaatDepartment of Medical Microbiology and Radboud Center for Infectious Diseases, Radboud University Medical Center, Nijmegen, the Netherlands.
M P A van MeerDepartment of Medical Microbiology and Immunology, Rijnstate Hospital, Arnhem, the Netherlands.
J Ten OeverDepartment of Internal Medicine and Radboud Center for Infectious Diseases, Radboud University Medical Center, P.O. Box 9101, 6500 HB, Nijmegen, the Netherlands.
E H GisolfDepartment of Internal Medicine, Rijnstate Hospital, Arnhem, the Netherlands.
Radboud University Medical Center · NLRadboud University Nijmegen · NLRijnstate Hospital · NL

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

purposeTo assess the likelihood of occult infection in patients with clinically unsuspected orthopedic implants during Staphylococcus aureus bacteremia (SAB).

methodsIn a retrospective study in two Dutch hospitals, we included all patients with SAB between 2013 and 2020 with one or more orthopedic implants in whom [

resultsFifty-five of 191 (29%) orthopedic implants in 118 SAB patients included had clinical signs of infection. Of all 136 unsuspected implants, 5 (3%, all arthroplasties), showed increased [

conclusionAlthough orthopedic implants are evidently a risk factor for metastatic infection during SAB, the absence of clinical symptoms obviate the need of additional investigations or prolonged antibiotic treatment.

Indexed as

BacteremiaMethicillin-Resistant Staphylococcus aureusStaphylococcal InfectionsFluorodeoxyglucose F18HumansPositron Emission Tomography Computed TomographyProstheses and ImplantsRetrospective StudiesStaphylococcus aureusFluorodeoxyglucose F18DiagnosticsFDG-PET/CTOrthopedic implantsStaphylococcus aureus bacteremia

Identifiers

PMID36076049
PMCPMC10205877
OpenAlexW4294993203

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.