Evidence map›Paper›PMID 36076044›Full record

Observational studyScientific reports2022

mHealth system (ATOPE+) to support exercise prescription in breast cancer survivors: a reliability and validity, cross-sectional observational study (ATOPE study).

Paula Postigo-Martin, Rocío Gil-Gutiérrez, Salvador Moreno-Gutiérrez, Maria Lopez-Garzon, Ángela González-Santos, Manuel Arroyo-Morales, Irene Cantarero-Villanueva

2 registry-linked trialsOpen access · goldAbstract readObservational Study
In one paragraph

Observational study in Scientific reports, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to 2 registered trials, which are not on this map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
0.7field-weighted citation impact, top 28% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT03787966 nacompletednot on this map

Attenuating Cancer Treatment-related Toxicity in Oncology Patients With a Tailored Physical Exercise Program: Study Protocol of the ATOPE Trial in Women Recently Diagnosed With Breast Cancer

TypeinterventionalSponsorUniversidad de GranadaRan2019 to 2025Enrolled100ConditionsBreast NeoplasmsArmsATOPE-B, ATOPE-I
NCT06518200 nanot yet recruitingnot on this mapstarted 2026, after this paper: background citation

ATOPE-PRO: Effects on the Prevention of Breast Cancer Therapy-related Cardiovascular Toxicity of a Daily-adapted and Individualized Program With Support From a Mobile Application

TypeinterventionalSponsorUniversidad de GranadaRan2026 to 2028Enrolled102ConditionsBreast Cancer FemaleArmsIndividualised health recommentations, General health recommendations, Individualised physical exercise program
3 · Its place in the literature

Who cites it

3 citing papers in PubMed, 7 citations in OpenAlex.

  1. Article
  2. Article
  3. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 2 institutions in 1 country.

Paula Postigo-MartinBiomedical Group (BIO277), University of Granada, Granada, Spain.
Rocío Gil-GutiérrezDepartment of Nursing, Faculty of Health Sciences, University of Granada, Avenida de la Ilustración, 60, 18016, Granada, Spain. rogilgu@ugr.es.
Salvador Moreno-GutiérrezDepartment of Computer Architecture and Technology, CITIC-UGR, Research Center, University of Granada, Granada, Spain.
Maria Lopez-GarzonBiomedical Group (BIO277), University of Granada, Granada, Spain.
Ángela González-SantosBiomedical Group (BIO277), University of Granada, Granada, Spain.
Manuel Arroyo-MoralesBiomedical Group (BIO277), University of Granada, Granada, Spain.
Irene Cantarero-VillanuevaBiomedical Group (BIO277), University of Granada, Granada, Spain.
Universidad de Granada · ESInstituto de Investigación Biosanitaria de Granada · ES

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Physical exercise is known to be beneficial for breast cancer survivors (BCS). However, avoiding nonfunctional overreaching is crucial in this population, as they are in physiological dysregulation. These factors could decrease their exercise capacity or facilitate nonfunctional overreaching, which can increase their risk of additional morbidities and even all-cause mortality. The focus of this study is to evaluate the reliability and validity of the ATOPE+ mHealth system to estimate autonomic balance and specific wellness parameters associated with BCS' perceived load, thereby informing nonlinear prescriptions in individualized physical exercise programs for BCS.Twenty-two BCS were included in the reliability and validity analysis. Measures were taken for four days, including morning autonomic balance by heart rate variability, self-reported perception of recovery from exercise, sleep satisfaction, emotional distress and fatigue after exertion. Measures were taken utilizing the ATOPE+ mHealth system application. The results of these measures were compared with criterion instruments to assess validity.The reliability results indicated that the intraclass correlation coefficient (ICC) showed an excellent correlation for recovery (0.93; 95% CI 0.85-0.96) and distress (0.94, 95% CI 0.89-0.97) as well as good correlation for the natural logarithm of the mean square root differences of the standard deviation (LnRMSSD) (0.87; 95% CI 0.74-0.94). Sleep satisfaction also showed an excellent correlation with a weighted kappa of 0.83. The validity results showed no significant differences, except for fatigue. ATOPE+ is reliable and valid for remotely assessing autonomic balance, perception of recovery, sleep satisfaction and emotional distress in BCS; however, it is not for fatigue. This highlights that ATOPE+ could be an easy and efficient system used to assess readiness in BCS, and could help to improve their health by supporting the prescription of optimal and safe physical exercise. Trial registration NCT03787966 ClinicalTrials.gov, December 2019 [ATOPE project]. https://clinicaltrials.gov/ct2/show/NCT03787966 .

Indexed as

Breast NeoplasmsCancer SurvivorsTelemedicineFatigueFemaleHumansPrescriptionsReproducibility of Results

Identifiers

PMID36076044
PMCPMC9458651
OpenAlexW4295080987

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.