Evidence map›Paper›PMID 36075904›Full record

ReviewNature reviews. Disease primers2022

Frozen shoulder.

Neal L Millar, Adam Meakins, Filip Struyf, Elaine Willmore, Abigail L Campbell, Paul D Kirwan, Moeed Akbar, Laura Moore, Jonathan C Ronquillo, George A C Murrell and 1 more

5 registry-linked trialsOpen access · greenAbstract readReview
PubMed Publisher
In one paragraph

Review in Nature reviews. Disease primers, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to 5 registered trials, which are not on this map. Cited by 98 papers, 7 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
98citing papers in PubMed, 7 pooled it
36.6field-weighted citation impact, top 1% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT05980572 nacompletednot on this map

Mobile Device Based Telerehabilitation for Frozen Shoulder-A Prospective Randomized Controlled Study.

TypeinterventionalSponsorChang Gung Memorial HospitalRan2022 to 2023Enrolled21ConditionsFrozen ShoulderArmsGlenohumeral joint and subacromial space triamcinolone injections, App-assisted exercise, Nonsteroidal anti-inflammatory drugs (aceclofenac)
NCT06229964 narecruitingnot on this mapstarted 2025, after this paper: background citation

A Double Blinded Randomized Controlled Trial (RCT) Exploring the Additional Effect of a Suprascapular Nerve Block in Combination With an Intra-Articular Corticosteroid Injection in Patients With Frozen Shoulder

TypeinterventionalSponsorUniversitair Ziekenhuis BrusselRan2025 to 2028Enrolled110ConditionsFrozen Shoulder, Adhesive CapsulitisArmsSSNB + IACI, Sham SSNB + IACI
NCT06494657 not yet recruitingnot on this mapstarted 2024, after this paper: background citation

Frozen Shoulder: A Pragmatic Replicated N-of-1 Case Series Investigating Glucose Levels and Patient Reported Outcomes Following a Corticosteroid Injection.

TypeobservationalSponsorCentral London Community Healthcare NHS TrustRan2024 to 2025Enrolled10ConditionsFrozen Shoulder, Adhesive CapsulitisArmsCorticosteroid injection
NCT06725823 narecruitingnot on this mapstarted 2025, after this paper: background citation

Therapeutic Effect of Shoulder Anterior Capsular Block (SHAC) Versus Suprascapular Nerve Block in Patients With Frozen Shoulder

TypeinterventionalSponsorSohag UniversityRan2025 to 2026Enrolled50ConditionsFrozen ShoulderArmssuprascapular nerve block group, shoulder anterior capsular block group
NCT07510737 not yet recruitingnot on this mapstarted 2026, after this paper: background citation

The Effect of Cross Training on Clinical and Functional Outcomes in Frozen Shoulder Rehabilitation

TypeobservationalSponsorInonu UniversityRan2026 to 2026Enrolled38ConditionsFrozen ShoulderArmsStandard Physical Therapy Group, Cross-Education Group
3 · Its place in the literature

Who cites it

98 citing papers in PubMed, 7 syntheses or guidelines pooled it, 183 citations in OpenAlex.

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  6. The diagnostic value of physical examination tests in adhesive capsulitis: a systematic review.European journal of physical and rehabilitation medicine · 2023
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  20. Assessment of the Validity and Reliability of the Turkish Version of the Modified Tampa Scale for Kinesiophobia in Patients With Shoulder Pain.Medical science monitor : international medical journal of experimental and clinical research · 2026
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38 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors at 9 institutions in 6 countries.

Neal L MillarSchool of Infection and Immunity, College of Medicine, Veterinary and Life Sciences, University of Glasgow, Glasgow, UK. neal.millar@glasgow.ac.uk.ORCID 0000-0001-9251-9907
Adam MeakinsDepartment of Trauma and Orthopaedics, West Hertfordshire Hospital Trust, Watford, UK.
Filip StruyfDepartment of Rehabilitation Sciences and Physiotherapy, University of Antwerp, Antwerp, Belgium.ORCID 0000-0002-9128-9684
Elaine WillmorePhysiotherapy Department, Gloucestershire Hospitals NHS Foundation Trust, Gloucester, UK.
Abigail L CampbellDepartment of Orthopaedic Surgery, Kaiser Permanente West Los Angeles, Los Angeles, CA, USA.ORCID 0000-0002-8903-8376
Paul D KirwanSchool of Medicine, Discipline of Physiotherapy, Trinity College Dublin, Dublin, Ireland.
Moeed AkbarSchool of Infection and Immunity, College of Medicine, Veterinary and Life Sciences, University of Glasgow, Glasgow, UK.ORCID 0000-0002-6923-4724
Laura MooreDepartment of Orthopaedic Surgery, Sports Medicine and Shoulder Service, Hospital for Special Surgery, New York, NY, USA.
Jonathan C RonquilloDe La Salle University Medical Center, Health Sciences Institute & Asian Hospital and Medical Center, Dasmariñas, Philippines.
George A C MurrellOrthopaedic Research Institute, St George Hospital, University of New South Wales, Sydney, New South Wales, Australia.ORCID 0000-0002-8251-1327
Scott A RodeoDepartment of Orthopaedic Surgery, Sports Medicine and Shoulder Service, Hospital for Special Surgery, New York, NY, USA.ORCID 0000-0002-0745-9880
Hospital for Special Surgery · USUniversity of Glasgow · GBAsian Hospital and Medical Center · PHGloucestershire Hospitals NHS Foundation Trust · GBKaiser Permanente West Los Angeles Medical Center · USTrinity College Dublin · IEUniversity of Antwerp · BEUNSW Sydney · AUWest Hertfordshire Hospitals NHS Trust · GB

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Frozen shoulder is a common debilitating disorder characterized by shoulder pain and progressive loss of shoulder movement. Frozen shoulder is frequently associated with other systemic conditions or occurs following periods of immobilization, and has a protracted clinical course, which can be frustrating for patients as well as health-care professionals. Frozen shoulder is characterized by fibroproliferative tissue fibrosis, whereby fibroblasts, producing predominantly type I and type III collagen, transform into myofibroblasts (a smooth muscle phenotype), which is accompanied by inflammation, neoangiogenesis and neoinnervation, resulting in shoulder capsular fibrotic contractures and the associated clinical stiffness. Diagnosis is heavily based on physical examination and can be difficult depending on the stage of disease or if concomitant shoulder pathology is present. Management consists of physiotherapy, therapeutic modalities such as steroid injections, anti-inflammatory medications, hydrodilation and surgical interventions; however, their effectiveness remains unclear. Facilitating translational science should aid in development of novel therapies to improve outcomes among individuals with this debilitating condition.

Indexed as

BursitisFibrosisHumansPhysical Therapy Modalities

Identifiers

PMID36075904
OpenAlexW4295088748

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.