Evidence map›Paper›PMID 36075560›Full record

Trial reportJournal of vascular and interventional radiology : JVIR2022

Accuracy and Safety of Scout Dose Resin Yttrium-90 Microspheres for Radioembolization Therapy Treatment Planning: A Prospective Single-Arm Clinical Trial.

Nima Kokabi, Linzi A Webster, Mohammad Elsayed, Jeffrey M Switchenko, Bernard Chen, David Brandon, James Galt, Ila Sethi, Mircea Cristescu, S Cheenu Kappadath and 1 more

2 registry-linked trialsAbstract readClinical Trial
In one paragraph

Trial report in Journal of vascular and interventional radiology : JVIR, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to 2 registered trials, which are not on this map. Cited by 13 papers.

0numbers the graph read from it
0cells of the map it votes in
13citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT04172714 nacompletednot on this map

Theragnostic Low Dose Y90 Microspheres for Personalized Y90 Radioembolization Dosimetry Planning

TypeinterventionalSponsorEmory UniversityRan2019 to 2021Enrolled30ConditionsHCC, Cancer of Liver, CancerArmsSIR-Spheres microspheres
NCT07476651 narecruitingnot on this mapstarted 2026, after this paper: background citation

Lung Shunt Fraction Measurement With Scout Dose of Resin Yttrium-90 Microspheres for Radioembolization (LASER)

TypeinterventionalSponsorSeoul National University HospitalRan2026 to 2029Enrolled30ConditionsRadioembolization, Hepatocellular Carcinoma (HCC), Intrahepatic Cholangiocarcinoma (ICC), Liver MetastasisArmsscout dose
3 · Its place in the literature

Who cites it

13 citing papers in PubMed.

  1. Trial
  2. Article
  3. Review
  4. Article
  5. Quantitative imaging in medicine and surgery · 2025
    Article
  6. Observational
  7. Article
  8. Expanding the long-axial field-of-view PET-CT horizons: unveiling new arrows in our quiver.European journal of nuclear medicine and molecular imaging · 2024
    Article
  9. Article
  10. Article
  11. New frontiers in radioembolization.Therapeutic advances in medical oncology · 2024
    Review
  12. Predictive value ofEJNMMI research · 2023
    Article
  13. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors.

Nima KokabiDivision of Interventional Radiology and Image-Guided Medicine, Department of Radiology and Imaging Sciences, Emory University School of Medicine, Atlanta, Georgia. Electronic address: nkokabi@emory.edu.
Linzi A WebsterDivision of Interventional Radiology and Image-Guided Medicine, Department of Radiology and Imaging Sciences, Emory University School of Medicine, Atlanta, Georgia.
Mohammad ElsayedDivision of Interventional Radiology and Image-Guided Medicine, Department of Radiology and Imaging Sciences, Emory University School of Medicine, Atlanta, Georgia.
Jeffrey M SwitchenkoDepartment of Biostatistics and Bioinformatics, Rollins School of Public Health, Emory University, Atlanta, Georgia.
Bernard ChenDivision of Interventional Radiology and Image-Guided Medicine, Department of Radiology and Imaging Sciences, Emory University School of Medicine, Atlanta, Georgia.
David BrandonDivision of Nuclear Medicine and Molecular Imaging, Department of Radiology and Imaging Sciences, Emory University School of Medicine, Atlanta, Georgia.
James GaltDivision of Nuclear Medicine and Molecular Imaging, Department of Radiology and Imaging Sciences, Emory University School of Medicine, Atlanta, Georgia.
Ila SethiDivision of Nuclear Medicine and Molecular Imaging, Department of Radiology and Imaging Sciences, Emory University School of Medicine, Atlanta, Georgia.
Mircea CristescuDivision of Interventional Radiology, Department of Radiology, Medical College of Wisconsin, Milwaukee, Wisconsin.
S Cheenu KappadathDivision of Diagnostic Imaging, Department of Imaging Physics, The University of Texas MD Anderson Cancer Center, Houston, Texas.
David M SchusterDivision of Nuclear Medicine and Molecular Imaging, Department of Radiology and Imaging Sciences, Emory University School of Medicine, Atlanta, Georgia.

Funding

Winship Cancer Institute Cancer Center Support GrantP30CA138292 · NCI · EMORY UNIVERSITY · PI Suresh S Ramalingam · 2009 to 2026
$47.5M
NCI NIH HHS P30 CA138292
6 · The paper itself

Abstract

purposeTo compare the accuracy and safety of 0.56 GBq resin yttrium-90 ( MATERIALS AND

methodsThis prospective single-arm clinical trial (Clinicaltrials.gov: NCT04172714) recruited patients with HCC. Patients underwent same-day mapping with MAA and scout

resultsThirty patients were treated using 19 segmental and 14 nonsegmental (ie, 2 contiguous segments or nonsegmental) therapies. MAA had weak LSF, moderate TNR, and moderate TD linear correlation with Rx

conclusionsCompared with MAA, scout

Indexed as

Carcinoma, HepatocellularEmbolization, TherapeuticLiver NeoplasmsHumansMicrospheresProspective StudiesRetrospective StudiesTechnetium Tc 99m Aggregated AlbuminTissue DistributionTomography, Emission-Computed, Single-PhotonYttrium RadioisotopesTechnetium Tc 99m Aggregated AlbuminYttrium-90Yttrium Radioisotopes

Identifiers

PMID36075560
PMCPMC9834905

What OpenQuestion holds

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Read underepoch 390

Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.