Evidence map›Paper›PMID 36075210›Full record

ArticleJournal of animal science2022

Sheep fecal transplantation affects growth performance in mouse models by altering gut microbiota.

Jiangbo Cheng, Xiaoxue Zhang, Deyin Zhang, Yukun Zhang, Xiaolong Li, Yuan Zhao, Dan Xu, Liming Zhao, Wenxin Li, Jianghui Wang and 10 more

Open access · greenAbstract read
In one paragraph

Article in Journal of animal science, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers.

0numbers the graph read from it
0cells of the map it votes in
7citing papers in PubMed
1.2field-weighted citation impact, top 22% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

7 citing papers in PubMed, 14 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

20 authors at 2 institutions in 1 country.

Jiangbo ChengThe State Key Laboratory of Grassland Agro-ecosystems, College of Pastoral Agriculture Science and Technology, Lanzhou University, Lanzhou, Gansu 730020, China.ORCID 0000-0002-1281-5157
Xiaoxue ZhangCollege of Animal Science and Technology, Gansu Agricultural University, Lanzhou, Gansu 730070, China.
Deyin ZhangThe State Key Laboratory of Grassland Agro-ecosystems, College of Pastoral Agriculture Science and Technology, Lanzhou University, Lanzhou, Gansu 730020, China.
Yukun ZhangThe State Key Laboratory of Grassland Agro-ecosystems, College of Pastoral Agriculture Science and Technology, Lanzhou University, Lanzhou, Gansu 730020, China.ORCID 0000-0003-0729-3267
Xiaolong LiThe State Key Laboratory of Grassland Agro-ecosystems, College of Pastoral Agriculture Science and Technology, Lanzhou University, Lanzhou, Gansu 730020, China.
Yuan ZhaoThe State Key Laboratory of Grassland Agro-ecosystems, College of Pastoral Agriculture Science and Technology, Lanzhou University, Lanzhou, Gansu 730020, China.
Dan XuCollege of Animal Science and Technology, Gansu Agricultural University, Lanzhou, Gansu 730070, China.
Liming ZhaoCollege of Animal Science and Technology, Gansu Agricultural University, Lanzhou, Gansu 730070, China.
Wenxin LiCollege of Animal Science and Technology, Gansu Agricultural University, Lanzhou, Gansu 730070, China.
Jianghui WangCollege of Animal Science and Technology, Gansu Agricultural University, Lanzhou, Gansu 730070, China.
Bubo ZhouCollege of Animal Science and Technology, Gansu Agricultural University, Lanzhou, Gansu 730070, China.
Changchun LinCollege of Animal Science and Technology, Gansu Agricultural University, Lanzhou, Gansu 730070, China.
Xiaobin YangCollege of Animal Science and Technology, Gansu Agricultural University, Lanzhou, Gansu 730070, China.
Rui ZhaiCollege of Animal Science and Technology, Gansu Agricultural University, Lanzhou, Gansu 730070, China.
Panpan CuiCollege of Animal Science and Technology, Gansu Agricultural University, Lanzhou, Gansu 730070, China.
Xiwen ZengCollege of Animal Science and Technology, Gansu Agricultural University, Lanzhou, Gansu 730070, China.
Yongliang HuangCollege of Animal Science and Technology, Gansu Agricultural University, Lanzhou, Gansu 730070, China.
Zongwu MaCollege of Animal Science and Technology, Gansu Agricultural University, Lanzhou, Gansu 730070, China.
Jia LiuCollege of Animal Science and Technology, Gansu Agricultural University, Lanzhou, Gansu 730070, China.
Weimin WangThe State Key Laboratory of Grassland Agro-ecosystems, College of Pastoral Agriculture Science and Technology, Lanzhou University, Lanzhou, Gansu 730020, China.
Gansu Agricultural University · CNLanzhou University · CN

Funding

Chinese Academy of SciencesKey R&D Program of Gansu Province 20YF3NA012National Key R&D Program of China 2021YFD1300901Western Young Scholars
6 · The paper itself

Abstract

Animal growth traits are important and complex traits that determine the productivity of animal husbandry. There are many factors that affect growth traits, among which diet digestion is the key factor. In the process of animal digestion and absorption, the role of gastrointestinal microbes is essential. In this study, we transplanted two groups of sheep intestinal microorganisms with different body weights into the intestines of mice of the same age to observe the effect of fecal bacteria transplantation on the growth characteristics of the mouse model. The results showed that receiving fecal microbiota transplantation (FMT) had an effect on the growth traits of recipient mice (P < 0.05). Interestingly, only mice receiving high-weight donor microorganisms showed differences. Use 16S rDNA sequencing technology to analyze the stool microorganisms of sheep and mice. The microbial analysis of mouse feces showed that receiving FMT could improve the diversity and richness of microorganisms (P < 0.05), and the microbial composition of mouse feces receiving low-weight donor microorganisms was similar to that of the control group, which was consistent with the change trend of growth traits. The feces of high-weight sheep may have higher colonization ability. The same five biomarkers were identified in the donor and recipient, all belonging to Firmicutes, and were positively correlated with the body weight of mice at each stage. These results suggest that FMT affects the growth traits of receptors by remodeling their gut microflora.

Indexed as

Fecal Microbiota TransplantationGastrointestinal MicrobiomeAnimalsBacteriaFecesGastrointestinal TractMiceSheep16S rDNA sequencingfecal microbial transplantationgrowth traitsmicrobial colonizationsheep

Identifiers

PMID36075210
PMCPMC9667978
OpenAlexW4295080341

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.