Evidence map›Paper›PMID 36074973›Full record

ReviewCirculation. Arrhythmia and electrophysiology2022

Sinus Tachycardia: a Multidisciplinary Expert Focused Review.

Kenneth A Mayuga, Artur Fedorowski, Fabrizio Ricci, Rakesh Gopinathannair, Jonathan Walter Dukes, Christopher Gibbons, Peter Hanna, Dan Sorajja, Mina Chung, David Benditt and 22 more

Open access · bronzeAbstract readReview
In one paragraph

Review in Circulation. Arrhythmia and electrophysiology, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 22 papers.

0numbers the graph read from it
0cells of the map it votes in
22citing papers in PubMed
9.6field-weighted citation impact, top 1% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

22 citing papers in PubMed, 50 citations in OpenAlex.

  1. Trial
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  15. Can standing replace upright tilt table testing in the diagnosis of postural tachycardia syndrome (POTS) in the young?Clinical autonomic research : official journal of the Clinical Autonomic Research Society · 2025
    Article
  16. Review
  17. Review
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

32 authors at 20 institutions in 5 countries.

Kenneth A MayugaSection of Cardiac Electrophysiology and Pacing, Department of Cardiovascular Medicine, Cleveland Clinic, OH (K.A.M.).ORCID 0000-0002-3434-9599
Artur FedorowskiKarolinska Institutet & Karolinska University Hospital, Stockholm, Sweden (A.F.).ORCID 0000-0002-5352-6327
Fabrizio RicciDepartment of Neuroscience, Imaging and Clinical Sciences, "G.d'Annunzio" University of Chieti-Pescara, Chieti Scalo, Italy (F.R.).ORCID 0000-0002-1401-6623
Rakesh GopinathannairKansas City Heart Rhythm Institute, Overland Park (R.G.).ORCID 0000-0003-4611-3687
Jonathan Walter DukesCommunity Memorial Hospital, Ventura, CA (J.W.D.).
Christopher GibbonsBeth Israel Deaconess Medical Center, Boston, MA (C.G.).
Peter HannaUniversity of California, Los Angeles (P.H.).ORCID 0000-0003-3092-5090
Dan SorajjaMayo Clinic Arizona (D.S.).ORCID 0000-0003-1976-6420
Mina ChungSection of Cardiac Electrophysiology and Pacing, Department of Cardiovascular Medicine, Cleveland Clinic, Cleveland, OH (M.C.).ORCID 0000-0002-7835-6045
David BendittUniversity of Minnesota Medical School, Minneapolis (D.B.).ORCID 0000-0002-8511-6920
Robert SheldonUniversity of Calgary, Canada (R.S.).ORCID 0000-0002-3463-4082
Mirna B AyacheMetroHealth Medical Center, Case Western Reserve University School of Medicine, Cleveland, OH (M.B.A.).
Hiba AbouAssiDivision of Endocrinology, Metabolism, and Nutrition, Duke University Medical Center, Durham, NC (H.A.A.).
Kalyanam ShivkumarUniversity of California, Los Angeles (K.S.).ORCID 0000-0002-4121-1766
Blair P GrubbThe University of Toledo Medical Center, OH (B.P.G.).
Mohamed H HamdanUniversity of Wisconsin, Madison (M.H.H.).
Stavros StavrakisUniversity of Oklahoma Health Science Center, Oklahoma City (S.S.).ORCID 0000-0002-4370-8135
Tamanna SinghDepartment of Cardiovascular Medicine, Cleveland Clinic, OH (T.S.).ORCID 0000-0002-9591-7860
Jeffrey J GoldbergerDivision of Cardiology, Department of Medicine, University of Miami, FL (J.J.G.).ORCID 0000-0001-9802-1851
James A S MuldowneyVanderbilt University Medical Center &Tennessee Valley Healthcare System, Nashville Campus, Department of Veterans Affairs, TN (J.A.S.M.).ORCID 0000-0001-7449-5868
Mark BelhamCambridge University Hospitals NHS FT, United Kingdom (M.B.).ORCID 0000-0002-8572-3501
David C KemUniversity of Oklahoma Health Sciences Center, Oklahoma City (D.C.K.).ORCID 0000-0001-8142-7767
Cem AkinUniversity of Michigan, Ann Arbor (C.A.).ORCID 0000-0001-6301-4520
Barbara K BruceMayo Clinic, Jacksonville, FL (B.K.B.).ORCID 0000-0003-2502-2428
Nicole E ZahkaCincinnati Children's Hospital Medical Center, OH (N.E.Z.).ORCID 0000-0003-3545-0370
Qi FuInstitute for Exercise and Environmental Medicine at Texas Health Presbyterian Hospital Dallas & University of Texas Southwestern Medical Center (Q.F.).ORCID 0000-0002-4218-9126
Erik H Van ItersonSection of Preventive Cardiology & Rehabilitation, Robert and Suzanne Tomsich Department of Cardiovascular Medicine, Miller Family Heart, Vascular & Thoracic Institute, Cleveland Clinic, OH (E.H.V.I.).ORCID 0000-0003-0576-3229
Satish R RajDepartment of Cardiac Sciences, Libin Cardiovascular Institute, Cumming School of Medicine, University of Calgary, Canada (S.R.R.).ORCID 0000-0002-5890-3785
Fetnat Fouad-TaraziCleveland Clinic, OH (F.F.-T.).
David S GoldsteinCNP/DIR/NINDS/NIH, Bethesda, MD (D.S.G.).
Julian StewartNew York Medical College, Hawthorne (J.S.).ORCID 0000-0002-6082-359X
Brian OlshanskyUniversity of Iowa (B.O.).ORCID 0000-0002-6044-045X
Cleveland Clinic · USUniversity of California, Los Angeles · USUniversity of Oklahoma Health Sciences Center · USAnvik Corporation (United States) · USBeth Israel Deaconess Medical Center · USCambridge University Hospitals NHS Foundation Trust · GBCincinnati Children's Hospital Medical Center · USDuke University · USHeart Rhythm Society · USJacksonville College · USKarolinska University Hospital · SELibin Cardiovascular Institute of Alberta · CAMayo Clinic in Arizona · USMemorial Health System · USMetroHealth Medical Center · USNational Institutes of Health · USTexas Health Dallas · USUniversity of Calgary · CAUniversity of Chieti-Pescara · ITUniversity of Iowa · US

Funding

Project 3 Genes to Omics-Informed Drugs: Drug Repositioning and Testing to Prevent AF ProgressionsP01HL158502 · NHLBI · CLEVELAND CLINIC LERNER COM-CWRU · PI Robert Alden Koeth · 2022 to 2026
$16.9M
Mechanisms of Parkinson Disease and Related DisordersZIANS003033 · NINDS · NATIONAL INSTITUTE OF NEUROLOGICAL DISORDERS AND STROKE · PI GOLDSTEIN, DAVID · 2009 to 2022
$8.2M
Functional Genomics of Atrial Fibrillation in Human AtriaR01HL111314 · NHLBI · CLEVELAND CLINIC LERNER COM-CWRU · PI BARNARD, JOHN, CHUNG, MINA KAY · 2012 to 2019
$6.1M
RADIOMIC APPROACHES TO IMPROVE TARGETING FOR ATRIAL FIBRILLATION CATHETER ABLATIONR01HL158071 · NHLBI · CLEVELAND CLINIC LERNER COM-CWRU · PI BARNARD, JOHN, CHUNG, MINA KAY · 2021 to 2024
$2.9M
BLRD VA IK6 BX006185Intramural NIH HHS ZIA NS003033NHLBI NIH HHS P01 HL158502NHLBI NIH HHS R01 HL111314NHLBI NIH HHS R01 HL158071
6 · The paper itself

Abstract

Sinus tachycardia (ST) is ubiquitous, but its presence outside of normal physiological triggers in otherwise healthy individuals remains a commonly encountered phenomenon in medical practice. In many cases, ST can be readily explained by a current medical condition that precipitates an increase in the sinus rate, but ST at rest without physiological triggers may also represent a spectrum of normal. In other cases, ST may not have an easily explainable cause but may represent serious underlying pathology and can be associated with intolerable symptoms. The classification of ST, consideration of possible etiologies, as well as the decisions of when and how to intervene can be difficult. ST can be classified as secondary to a specific, usually treatable, medical condition (eg, pulmonary embolism, anemia, infection, or hyperthyroidism) or be related to several incompletely defined conditions (eg, inappropriate ST, postural tachycardia syndrome, mast cell disorder, or post-COVID syndrome). While cardiologists and cardiac electrophysiologists often evaluate patients with symptoms associated with persistent or paroxysmal ST, an optimal approach remains uncertain. Due to the many possible conditions associated with ST, and an overlap in medical specialists who see these patients, the inclusion of experts in different fields is essential for a more comprehensive understanding. This article is unique in that it was composed by international experts in Neurology, Psychology, Autonomic Medicine, Allergy and Immunology, Exercise Physiology, Pulmonology and Critical Care Medicine, Endocrinology, Cardiology, and Cardiac Electrophysiology in the hope that it will facilitate a more complete understanding and thereby result in the better care of patients with ST.

Indexed as

COVID-19Postural Orthostatic Tachycardia SyndromeHumansTachycardia, Sinusautonomic dysfunctionhyperthyroidisminappropriate sinus tachycardiapost-COVID syndromepostural orthostatic tachycardia syndromesinus tachycardia

Identifiers

PMID36074973
PMCPMC9523592
OpenAlexW4294982945

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.