Evidence map›Paper›PMID 36074939›Full record

ArticleBrain connectivity2023

Correlative Chemical Imaging Identifies Amyloid Peptide Signatures of Neuritic Plaques and Dystrophy in Human Sporadic Alzheimer's Disease.

Srinivas Koutarapu, Junyue Ge, Durga Jha, Kaj Blennow, Henrik Zetterberg, Tammaryn Lashley, Wojciech Michno, Jörg Hanrieder

Abstract read
In one paragraph

Article in Brain connectivity, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers.

0numbers the graph read from it
0cells of the map it votes in
7citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

7 citing papers in PubMed.

  1. Article
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  4. Review
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Srinivas KoutarapuDepartment of Psychiatry and Neurochemistry, Sahlgrenska Academy, University of Gothenburg, Mölndal, Sweden.
Junyue GeDepartment of Psychiatry and Neurochemistry, Sahlgrenska Academy, University of Gothenburg, Mölndal, Sweden.
Durga JhaDepartment of Psychiatry and Neurochemistry, Sahlgrenska Academy, University of Gothenburg, Mölndal, Sweden.
Kaj BlennowDepartment of Psychiatry and Neurochemistry, Sahlgrenska Academy, University of Gothenburg, Mölndal, Sweden.
Henrik ZetterbergDepartment of Psychiatry and Neurochemistry, Sahlgrenska Academy, University of Gothenburg, Mölndal, Sweden.ORCID 0000-0003-3930-4354
Tammaryn LashleyDepartment of Neurodegenerative Disease, Institute of Neurology, University College London, London, United Kingdom.
Wojciech MichnoDepartment of Psychiatry and Neurochemistry, Sahlgrenska Academy, University of Gothenburg, Mölndal, Sweden.ORCID 0000-0002-3096-3604
Jörg HanriederDepartment of Psychiatry and Neurochemistry, Sahlgrenska Academy, University of Gothenburg, Mölndal, Sweden.ORCID 0000-0001-6059-198X

Funding

Understanding Amyloid Pathology - Multiomic Activity Imaging of Plaque Formation Dynamics (AmyMAP)R01AG078796 · NIA · NORTHWESTERN UNIVERSITY AT CHICAGO · PI Jeffrey Nicholas Savas · 2022 to 2026
$2.7M
Human in vivo stable isotope labeling kinetics (iSILK) to quantify brain amyloid plaque kineticsR21AG078538 · NIA · WASHINGTON UNIVERSITY · PI HANRIEDER, JORG, SCHWETYE, KATHERINE · 2022 to 2022
$411k
Insights into Amyloid Pathogenicity DynamicsR21AG080705 · NIA · NORTHWESTERN UNIVERSITY AT CHICAGO · PI HANRIEDER, JORG, SAVAS, JEFFREY NICHOLAS · 2023 to 2024
$401k
NIA NIH HHS R21 AG078538NIA NIH HHS R21 AG080705
6 · The paper itself

Abstract

PubMed holds no abstract for this paper.

Indexed as

Alzheimer DiseaseNeurodegenerative DiseasesAmyloid beta-PeptidesAnimalsBrainHumansMagnetic Resonance ImagingMiceMice, TransgenicPlaque, AmyloidAmyloid beta-PeptidesAlzheimer's diseasebeta-amyloidcored plaquesdystrophic neuritismatrix-assisted laser/desorption ionization mass spectrometry imagingneuritic plaques

Identifiers

PMID36074939
PMCPMC10398722

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.