Evidence map›Paper›PMID 36074778›Full record

ReviewPLoS computational biology2022

Connectivity concepts in neuronal network modeling.

Johanna Senk, Birgit Kriener, Mikael Djurfeldt, Nicole Voges, Han-Jia Jiang, Lisa Schüttler, Gabriele Gramelsberger, Markus Diesmann, Hans E Plesser, Sacha J van Albada

Abstract readReview
In one paragraph

Review in PLoS computational biology, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 19 papers.

0numbers the graph read from it
0cells of the map it votes in
19citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

19 citing papers in PubMed.

  1. Article
  2. Article
  3. WhenAPL bioengineering · 2025
    Review
  4. Building on models-a perspective for computational neuroscience.Cerebral cortex (New York, N.Y. : 1991) · 2025
    Article
  5. Article
  6. Article
  7. Article
  8. Article
  9. Article
  10. Article
  11. Article
  12. Multi-scale spiking network model of human cerebral cortex.Cerebral cortex (New York, N.Y. : 1991) · 2024
    Article
  13. Article
  14. Article
  15. Article
  16. Article
  17. Article
  18. Article
  19. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors.

Johanna SenkInstitute of Neuroscience and Medicine (INM-6) and Institute for Advanced Simulation (IAS-6) and JARA-Institut Brain Structure-Function Relationships (INM-10), Jülich Research Centre, Jülich, Germany.ORCID 0000-0002-6304-062X
Birgit KrienerInstitute of Basic Medical Sciences, University of Oslo, Oslo, Norway.
Mikael DjurfeldtPDC Center for High-Performance Computing, KTH Royal Institute of Technology, Stockholm, Sweden.
Nicole VogesINT UMR 7289, Aix-Marseille University, Marseille, France.ORCID 0000-0002-6324-2600
Han-Jia JiangInstitute of Neuroscience and Medicine (INM-6) and Institute for Advanced Simulation (IAS-6) and JARA-Institut Brain Structure-Function Relationships (INM-10), Jülich Research Centre, Jülich, Germany.ORCID 0000-0002-9633-2573
Lisa SchüttlerChair of Theory of Science and Technology, Human Technology Center, RWTH Aachen University, Aachen, Germany.ORCID 0000-0001-7938-5967
Gabriele GramelsbergerChair of Theory of Science and Technology, Human Technology Center, RWTH Aachen University, Aachen, Germany.
Markus DiesmannInstitute of Neuroscience and Medicine (INM-6) and Institute for Advanced Simulation (IAS-6) and JARA-Institut Brain Structure-Function Relationships (INM-10), Jülich Research Centre, Jülich, Germany.ORCID 0000-0002-2308-5727
Hans E PlesserInstitute of Neuroscience and Medicine (INM-6) and Institute for Advanced Simulation (IAS-6) and JARA-Institut Brain Structure-Function Relationships (INM-10), Jülich Research Centre, Jülich, Germany.ORCID 0000-0001-7843-5993
Sacha J van AlbadaInstitute of Neuroscience and Medicine (INM-6) and Institute for Advanced Simulation (IAS-6) and JARA-Institut Brain Structure-Function Relationships (INM-10), Jülich Research Centre, Jülich, Germany.ORCID 0000-0003-0682-4855

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Sustainable research on computational models of neuronal networks requires published models to be understandable, reproducible, and extendable. Missing details or ambiguities about mathematical concepts and assumptions, algorithmic implementations, or parameterizations hinder progress. Such flaws are unfortunately frequent and one reason is a lack of readily applicable standards and tools for model description. Our work aims to advance complete and concise descriptions of network connectivity but also to guide the implementation of connection routines in simulation software and neuromorphic hardware systems. We first review models made available by the computational neuroscience community in the repositories ModelDB and Open Source Brain, and investigate the corresponding connectivity structures and their descriptions in both manuscript and code. The review comprises the connectivity of networks with diverse levels of neuroanatomical detail and exposes how connectivity is abstracted in existing description languages and simulator interfaces. We find that a substantial proportion of the published descriptions of connectivity is ambiguous. Based on this review, we derive a set of connectivity concepts for deterministically and probabilistically connected networks and also address networks embedded in metric space. Beside these mathematical and textual guidelines, we propose a unified graphical notation for network diagrams to facilitate an intuitive understanding of network properties. Examples of representative network models demonstrate the practical use of the ideas. We hope that the proposed standardizations will contribute to unambiguous descriptions and reproducible implementations of neuronal network connectivity in computational neuroscience.

Indexed as

Models, NeurologicalNeurosciencesComputer SimulationNeuronsSoftware

Identifiers

PMID36074778
PMCPMC9455883

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.