Evidence map›Paper›PMID 36074468›Full record

ArticleJAMA network open2022

Analysis of Heavy Rainfall in Sub-Saharan Africa and HIV Transmission Risk, HIV Prevalence, and Sexually Transmitted Infections, 2005-2017.

Jason M Nagata, Karly Hampshire, Adrienne Epstein, Feng Lin, Jennifer Zakaras, Pamela Murnane, Edwin D Charlebois, Alexander C Tsai, Denis Nash, Sheri D Weiser

Open access · goldAbstract read
In one paragraph

Article in JAMA network open, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 18 papers.

0numbers the graph read from it
0cells of the map it votes in
18citing papers in PubMed
7.8field-weighted citation impact, top 2% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

18 citing papers in PubMed, 30 citations in OpenAlex.

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  7. Exploring Socioeconomic Factors Among Women Living with HIV in Malawi and Kenya.Journal of racial and ethnic health disparities · 2026
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4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

10 authors at 4 institutions in 2 countries.

Jason M NagataDepartment of Pediatrics, University of California, San Francisco.
Karly HampshireDepartment of Medicine, University of California, San Francisco.
Adrienne EpsteinDepartment of Vector Biology, Liverpool School of Tropical Medicine, Liverpool, United Kingdom.
Feng LinDepartment of Epidemiology and Biostatistics, University of California, San Francisco.
Jennifer ZakarasDepartment of Medicine, University of California, San Francisco.
Pamela MurnaneDepartment of Epidemiology and Biostatistics, University of California, San Francisco.
Edwin D CharleboisDepartment of Medicine, University of California, San Francisco.
Alexander C TsaiCenter for Global Health and Mongan Institute, Massachusetts General Hospital, Boston.
Denis NashInstitute for Implementation Science in Population Health, City University of New York, New York.
Sheri D WeiserDepartment of Medicine, University of California, San Francisco.
University of California, San Francisco · USCenter for Global Health · USCity University of New York · USLiverpool School of Tropical Medicine · GB

Funding

Ujima Mentoring ProgramP30MH062246 · NIMH · UNIVERSITY OF CALIFORNIA, SAN FRANCISCO · PI MALLORY O JOHNSON · 2001 to 2026
$57.4M
Implementing a risk score to facilitate enhanced adherence support for pregnant and postpartum women at risk of viremiaK01MH119910 · NIMH · UNIVERSITY OF CALIFORNIA, SAN FRANCISCO · PI MURNANE, PAMELA MAE · 2019 to 2023
$922k
Informing national guidelines on adolescent and young adult physical activity and sedentary behavior to prevent cardiovascular diseaseK08HL159350 · NHLBI · UNIVERSITY OF CALIFORNIA, SAN FRANCISCO · PI NAGATA, JASON M · 2021 to 2025
$869k
NHLBI NIH HHS K08 HL159350NIMH NIH HHS K01 MH119910NIMH NIH HHS P30 MH062246
6 · The paper itself

Abstract

Importance: Extreme precipitation, including heavy rains and flooding, is associated with poor health outcomes mediated in part by decreases in income and food production. However, the association between heavy rains and HIV burden is unknown. Objective: To investigate the association between heavy rainfall, HIV prevalence, and HIV transmission risk over a 12-year span in sub-Saharan Africa. Design, Setting, and Participants: A cross-sectional population-based study, using data collected from the 2005-2017 Demographic and Health Surveys, was conducted in 21 countries in sub-Saharan Africa and analyzed from July 29, 2021, to June 14, 2022. Exposures: Heavy rainfall was defined based on the extent to which annual rainfall deviated from the historical average (standardized precipitation index ≥1.5) at the enumeration area level. Main Outcomes and Measures: HIV, self-reported sexually transmitted infections (STIs), and number of sexual partners. Results: The study included 288 333 participants aged 15 to 59 years; 172 344 were women (59.8%), and 183 378 were married (63.6%). Mean (SD) age was 31.9 (10.0) years. Overall, 42.4% of participants were exposed to at least 1 year of heavy rainfall in the past 10 years. Each year of heavy rainfall was associated with 1.14 (95% CI, 1.11-1.18) times the odds of HIV infection and 1.11 (95% CI, 1.07-1.15) times the odds of an STI in the past 12 months. There was also an association between heavy rainfall and the reported number of sexual partners (incident rate ratio, 1.12; 95% CI, 1.10-1.15). The odds were greater for the association between heavy rainfall and HIV prevalence and STIs among participants aged older than 20 years and participants in rural areas. Conclusions and Relevance: The findings of this study suggest that heavy rainfall was associated with a higher HIV burden in sub-Saharan Africa. The association between heavy rainfall and STIs and number of sexual partners suggests that an increase in the risk of sexual transmission is a plausible mechanism for the observed findings around HIV prevalence. Heavy rainfall could also worsen food insecurity, increasing the risk of transactional sex, or cause damage to public health infrastructure, reducing access to STI education, HIV testing, and treatment.

Indexed as

HIV InfectionsSexually Transmitted DiseasesAfrica South of the SaharaCross-Sectional StudiesFemaleHumansMalePrevalence

Identifiers

PMID36074468
PMCPMC9459663
OpenAlexW4294958706

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.