Evidence map›Paper›PMID 36074233›Full record

ArticleMolecular neurobiology2022

Neuroprotective Effects of a Cardioplegic Combination (Adenosine, Lidocaine, and Magnesium) in an Ischemic Stroke Model.

Yi-Chia Wang, Yih-Sharng Chen, Sung-Tsang Hsieh

Abstract read
PubMed Publisher
In one paragraph

Article in Molecular neurobiology, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed, 1 pooled it
1.3field-weighted citation impact, top 20% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed, 1 synthesis or guideline pooled it, 9 citations in OpenAlex.

  1. Pooled it
  2. Review
  3. Delayed Surgery and Adenosine, Lidocaine, and MgThe American journal of sports medicine · 2025
    Article
  4. Article
  5. Review
  6. Adenosine, lidocaine and MgFrontiers in medicine · 2023
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors at 2 institutions in 1 country.

Yi-Chia WangDepartment of Anesthesiology, National Taiwan University College of Medicine and National University Hospital, Taipei, Taiwan.
Yih-Sharng ChenDepartment of Surgery, National Taiwan University College of Medicine and National University Hospital, Taipei, Taiwan.
Sung-Tsang HsiehGraduate Institutes of Anatomy and Cell Biology, National Taiwan University College of Medicine, 1 Jen-Ai Road, Section 1, Taipei, 100233, Taiwan. shsieh@ntu.edu.tw.ORCID http://orcid.org/0000-0002-3188-8482
National Taiwan University · TWNational Taiwan University Hospital · TW

Funding

Ministry of Science and Technology, Taiwan 107-2314-B-002-043-MY3Ministry of Science and Technology, Taiwan 109-2314-B-002-243
6 · The paper itself

Abstract

Adenosine, lidocaine, and magnesium (ALM) are clinically available cardioplegic solutions. We examined the effects of low-dose ALM on ischemic stroke in cell and animal models. Cobalt chloride (CoCl

Indexed as

Ischemic StrokeNeuroblastomaNeuroprotective AgentsStrokeAdenosineAnimalsCardioplegic SolutionsCobaltDisease Models, AnimalGlucoseHumansLidocaineMagnesiumOxygenRatsAdenosineCardioplegic SolutionsCobaltcobaltous chlorideGlucoseLidocaineMagnesiumNeuroprotective AgentsOxygenAdenosine, lidocaine, and magnesiumCobalt chlorideIschemiaMiddle cerebral artery occlusionStroke

Identifiers

PMID36074233
OpenAlexW4294992397

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.