Evidence map›Paper›PMID 36074232›Full record

ArticleMolecular neurobiology2022

A1 Adenosine Receptor Activation Inhibits P2X3 Receptor-Mediated ATP Currents in Rat Dorsal Root Ganglion Neurons.

Jia-Wei Hao, Wen-Long Qiao, Qing Li, Shuang Wei, Xue-Mei Li, Ting-Ting Liu, Chun-Yu Qiu, Wang-Ping Hu

Abstract read
PubMed Publisher
In one paragraph

Article in Molecular neurobiology, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
0.6field-weighted citation impact, top 35% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed, 5 citations in OpenAlex.

  1. Article
  2. Article
  3. Targeting sensory neuron GPCRs for peripheral neuropathic pain.Trends in pharmacological sciences · 2023
    Review
  4. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 2 institutions in 1 country.

Jia-Wei HaoSchool of Basic Medical Sciences, Xianning Medical College, Hubei University of Science and Technology, 88 Xianning Road, Xianning, 437100, Hubei, People's Republic of China.
Wen-Long QiaoSchool of Basic Medical Sciences, Xianning Medical College, Hubei University of Science and Technology, 88 Xianning Road, Xianning, 437100, Hubei, People's Republic of China.
Qing LiSchool of Basic Medical Sciences, Xianning Medical College, Hubei University of Science and Technology, 88 Xianning Road, Xianning, 437100, Hubei, People's Republic of China.
Shuang WeiSchool of Basic Medical Sciences, Xianning Medical College, Hubei University of Science and Technology, 88 Xianning Road, Xianning, 437100, Hubei, People's Republic of China.
Xue-Mei LiSchool of Basic Medical Sciences, Xianning Medical College, Hubei University of Science and Technology, 88 Xianning Road, Xianning, 437100, Hubei, People's Republic of China.
Ting-Ting LiuSchool of Basic Medical Sciences, Xianning Medical College, Hubei University of Science and Technology, 88 Xianning Road, Xianning, 437100, Hubei, People's Republic of China.
Chun-Yu QiuSchool of Basic Medical Sciences, Xianning Medical College, Hubei University of Science and Technology, 88 Xianning Road, Xianning, 437100, Hubei, People's Republic of China.
Wang-Ping HuSchool of Basic Medical Sciences, Xianning Medical College, Hubei University of Science and Technology, 88 Xianning Road, Xianning, 437100, Hubei, People's Republic of China. wangping_hu@163.com.ORCID http://orcid.org/0000-0003-1870-325X
Hubei University of Science and Technology · CNHubei University of Chinese Medicine · CN

Funding

National Natural Science Foundation of China 81671101
6 · The paper itself

Abstract

Purinergic signaling is involved in multiple pain processes. P2X3 receptor is a key target in pain therapeutics, while A1 adenosine receptor signaling plays a role in analgesia. However, it remains unclear whether there is a link between them in pain. The present results showed that the A1 adenosine receptor agonist N

Indexed as

Ganglia, SpinalReceptors, Purinergic P2X3AdenosineAdenosine TriphosphateAdenylyl CyclasesAnalgesicsAnimalsColforsinNeuronsPainPertussis ToxinPurinergic P1 Receptor AgonistsPurinergic P1 Receptor AntagonistsRatsReceptors, Purinergic P1AdenosineAdenosine TriphosphateAdenylyl CyclasesAnalgesicsColforsinPertussis ToxinPurinergic P1 Receptor AgonistsPurinergic P1 Receptor AntagonistsReceptors, Purinergic P1Receptors, Purinergic P2X3A1 adenosine receptorDorsal root ganglion neuronElectrophysiologyNociceptive behaviorP2X3 receptor

Identifiers

PMID36074232
OpenAlexW4294991391

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.