Evidence map›Paper›PMID 36074213›Full record

ArticleCell and tissue banking2023

Improvement of human sperm properties with platelet-rich plasma as a cryoprotectant supplement.

Maryam Sadat Nabavinia, Arash Yari, Saeed Ghasemi-Esmailabad, Aida Gholoobi, Lida Gholizadeh, Ali Nabi, Marzieh Lotfi, Mohammad Ali Khalili

Registry-linked trialAbstract read
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In one paragraph

Article in Cell and tissue banking, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT07504575 (Effect of Platelet-rich Plasma), which is not on this map. Cited by 15 papers, 3 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
15citing papers in PubMed, 3 pooled it
3.9field-weighted citation impact, top 6% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT07504575 recruitingnot on this mapstarted 2026, after this paper: background citation

Effect of Platelet-rich Plasma (PRP) on the Quality of Donor Semen During Cryopreservation

TypeobservationalSponsorInstituto Valenciano de Infertilidad, IVI AlicanteRan2026 to 2028Enrolled20ConditionsSperm Cryodamage
3 · Its place in the literature

Who cites it

15 citing papers in PubMed, 3 syntheses or guidelines pooled it, 22 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 4 institutions in 1 country.

Maryam Sadat NabaviniaDepartment of Pharmacognosy, Faculty of Pharmacy and Pharmaceutical Sciences Research Center, Shahid Sadoughi University of Medical Sciences, Yazd, Iran.ORCID http://orcid.org/0000-0002-2086-0273
Arash YariPharmacy and Pharmaceutical Sciences Research Center, Shahid Sadoughi University of Medical Sciences, Yazd, Iran.
Saeed Ghasemi-EsmailabadDepartment of Tissue Engineering and Regenerative Medicine, Faculty of Advanced Technologies in Medicine, Iran University of Medical Sciences, Tehran, Iran.ORCID http://orcid.org/0000-0002-9652-8699
Aida GholoobiMedical Genetics Research Center, Mashhad University of Medical Science, Mashhad, Iran.
Lida GholizadehInfertility Center, Department of Obstetrics and Gynecology, Mazandaran University of Medical Sciences, Sari, Iran.
Ali NabiAndrology Research Center, Yazd Reproductive Sciences Institute, Shahid Sadoughi University of Medical Sciences, Yazd, Iran.
Marzieh LotfiAbortion Research Center, Yazd Reproductive Sciences Institute, Shahid Sadoughi university of medical sciences, Yazd, Iran. marzeih.lotfi@gmail.com.
Mohammad Ali KhaliliReproductive Science Institute, Shahid Sadoughi University of Medical Science, Yazd, Iran. khalili59@hotmail.com.ORCID http://orcid.org/0000-0002-6306-7881
Shahid Sadoughi University of Medical Sciences and Health Services · IRIran University of Medical Sciences · IRMashhad University of Medical Sciences · IRMazandaran University of Medical Sciences · IR

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

purposePlatelet-rich plasma (PRP) is a remarkable substance, which involves the growth and proliferation of all cell types. As a source of growth factors, we evaluated whether sperm cryopreservation supplemented with PRP improves the rates of sperm motility, viability, and DNA integrity after vitrification compared with conventional cryo-medium. MATERIALS AND

methods20 normal semen specimens were collected from healthy men. After swim-up preparation, each sample was divided into four aliquots. One, as control, received no treatment, and the other three experimental samples were treated with three different concentrations of PRP as cryoprotectant. Sperm parameters were examined before and after freezing procedure.

resultsPRP had no significant effect on sperm count. Meanwhile, the percentage of sperm progressive motility and viability in the PRP treated samples with 1×10

conclusionsThis study showed a protective effect of PRP on human sperm quality at an optimized concentration after vitrification. Besides, the effects of PRP supplementation of sperms on successful fertility following sperm preservation will be of interest.

Indexed as

Platelet-Rich PlasmaSemenCryoprotective AgentsDietary SupplementsHumansMaleSpermatozoaSperm MotilityCryoprotective AgentsCryoprotectant mediumPlatelet-rich plasmaSperm parametersVitrification

Identifiers

PMID36074213
OpenAlexW4294992469

What OpenQuestion holds

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Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.