Evidence map›Paper›PMID 36074194›Full record

ArticleClinical autonomic research : official journal of the Clinical Autonomic Research Society2022

Utricular dysfunction in patients with orthostatic hypotension.

Jae-Gyum Kim, Jeong-Heon Lee, Sun-Uk Lee, Jeong-Yoon Choi, Byung-Jo Kim, Ji-Soo Kim

Abstract read
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Article in Clinical autonomic research : official journal of the Clinical Autonomic Research Society, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 12 papers.

0numbers the graph read from it
0cells of the map it votes in
12citing papers in PubMed
4.4field-weighted citation impact, top 5% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

12 citing papers in PubMed, 20 citations in OpenAlex.

  1. Vestibulo-sympathetic interaction and otolith function in postural orthostatic tachycardia syndrome.Clinical autonomic research : official journal of the Clinical Autonomic Research Society · 2026
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  11. A study of otolith function in patients with orthostatic dizziness.European archives of oto-rhino-laryngology : official journal of the European Federation of Oto-Rhino-Laryngological Societies (EUFOS) : affiliated with the German Society for Oto-Rhino-Laryngology - Head and Neck Surgery · 2023
    Article
  12. The role of otolith reflexes in orthostatic intolerance.Clinical autonomic research : official journal of the Clinical Autonomic Research Society · 2022
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 3 institutions in 1 country.

Jae-Gyum KimDepartment of Neurology, Korea University Medical Center, 73 Goryeodae-ro, Seongbuk-gu, Seoul, 02841, South Korea.
Jeong-Heon LeeDepartment of Neurology, Korea University Medical Center, 73 Goryeodae-ro, Seongbuk-gu, Seoul, 02841, South Korea.
Sun-Uk LeeDepartment of Neurology, Korea University Medical Center, 73 Goryeodae-ro, Seongbuk-gu, Seoul, 02841, South Korea. sulee716@gmail.com.ORCID 0000-0001-8660-7759
Jeong-Yoon ChoiDepartment of Neurology, Seoul National University College of Medicine, Seoul, South Korea.
Byung-Jo KimDepartment of Neurology, Korea University Medical Center, 73 Goryeodae-ro, Seongbuk-gu, Seoul, 02841, South Korea.
Ji-Soo KimDepartment of Neurology, Seoul National University College of Medicine, Seoul, South Korea.
Seoul National University · KRKorea University Medical Center · KRKorea University · KR

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

purposeTo delineate the association between otolithic dysfunction and orthostatic hypotension (OH).

methodsWe retrospectively reviewed the medical records of 382 patients who presented with orthostatic dizziness at a tertiary dizziness center between July 2017 and December 2021. Patients were included for analyses when they had completed ocular (oVEMP) and/or cervical vestibular-evoked myogenic potentials (cVEMP), and head-up tilt table test with a Finometer (n = 155). We compared the results between the patients with OH (n = 38) and those with NOI (normal head-up tilt table test despite orthostatic intolerance, n = 117).

resultsThirty-eight patients with OH were further categorized as either classic (n = 30), delayed (n = 7), or initial (n = 1) types. Multivariable logistic regression showed that OH was associated with high baseline systolic BP (p = 0.046), presence of heart failure (p = 0.016), and unilateral oVEMP abnormalities (p = 0.016). n1 latency of oVEMP were negatively correlated with the maximal changes of systolic blood pressure (BP) in 15 s ([Formula: see text]SBP

conclusionsOur study provides evidence of utricular dysfunction related to OH.

Indexed as

Autonomic Nervous System DiseasesHypotension, OrthostaticVestibular Evoked Myogenic PotentialsDizzinessHumansRetrospective StudiesTilt-Table TestAutonomic nervous systemOrthostatic hypotensionOtolith

Identifiers

PMID36074194
OpenAlexW4294990962

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.