Evidence map›Paper›PMID 36074179›Full record

ArticleWiener klinische Wochenschrift2022

Allergic sensitization pattern as a marker of bronchial hyperresponsiveness in allergic rhinitis patients living in temperate continental climate zone.

Slavomír Perečinský, Lenka Murínová, Andrea Jančová, Pavol Murín, Katarína Perečinská, Marek Varga, Bronislava Víchová, Erik Pačuta, Mária Rašiová, Ľubomír Legáth

Abstract read
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In one paragraph

Article in Wiener klinische Wochenschrift, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
0.7field-weighted citation impact, top 33% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed, 5 citations in OpenAlex.

  1. Article
  2. Article
  3. Article
  4. [Risk factors for the development of airway hyperresponsiveness in patients with allergic rhinitis].Lin chuang er bi yan hou tou jing wai ke za zhi = Journal of clinical otorhinolaryngology head and neck surgery · 2023
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors at 2 institutions in 1 country.

Slavomír PerečinskýDepartment of Occupational Medicine and Clinical Toxicology, Medical Faculty of Pavol Jozef Šafárik University, Louis Pasteur University Hospital, Rastislavova 43, 041 90, Košice, Slovakia. slavomir.perecinsky@upjs.sk.ORCID http://orcid.org/0000-0002-1644-4824
Lenka MurínováDepartment of Occupational Medicine and Clinical Toxicology, Medical Faculty of Pavol Jozef Šafárik University, Louis Pasteur University Hospital, Rastislavova 43, 041 90, Košice, Slovakia.
Andrea JančováDepartment of Occupational Medicine and Clinical Toxicology, Medical Faculty of Pavol Jozef Šafárik University, Louis Pasteur University Hospital, Rastislavova 43, 041 90, Košice, Slovakia.
Pavol Murín1st Department of Cardiology, East-Slovak Institute of Cardiovascular Diseases and Medical Faculty of Pavol Jozef Safarik University, Ondavská 8, 04011, Košice, Slovakia.
Katarína PerečinskáDepartment of Occupational Medicine and Clinical Toxicology, Medical Faculty of Pavol Jozef Šafárik University, Louis Pasteur University Hospital, Rastislavova 43, 041 90, Košice, Slovakia.
Marek VargaDepartment of Occupational Medicine and Clinical Toxicology, Medical Faculty of Pavol Jozef Šafárik University, Louis Pasteur University Hospital, Rastislavova 43, 041 90, Košice, Slovakia.
Bronislava VíchováInstitute of Parasitology, Slovak Academy of Sciences, Department of Vector-Borne Diseases, Hlinkova 3, 040 01, Košice, Slovakia.
Erik PačutaDepartment of Occupational Medicine and Clinical Toxicology, Medical Faculty of Pavol Jozef Šafárik University, Louis Pasteur University Hospital, Rastislavova 43, 041 90, Košice, Slovakia.
Mária RašiováDepartment of Angiology, East Slovak Institute of Cardiovascular Diseases, Medical Faculty of Pavol Jozef Šafárik University, Ondavská 8, 040 11, Košice, Slovakia.
Ľubomír LegáthDepartment of Occupational Medicine and Clinical Toxicology, Medical Faculty of Pavol Jozef Šafárik University, Louis Pasteur University Hospital, Rastislavova 43, 041 90, Košice, Slovakia.
University of Pavol Jozef Šafárik · SKSlovak Academy of Sciences · SK

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundBronchial hyperresponsiveness (BHR) is a key feature of asthma, but it may also appear in allergic rhinitis. The type of allergen, as well as regional characteristics, play an important role in the development of BHR. The aim of our study was to analyze allergen sensitization patterns and the factors that affect BHR in allergic rhinitis patients living in temperate continental climate zone.

methodsThis study retrospectively analyzed allergic rhinitis patients from Eastern Slovakia who underwent skin-prick tests to aeroallergens, spirometry, histamine and methacholine bronchial provocation tests for evaluation of lower airway symptoms. We analyzed the associations between BHR and the pattern of aeroallergen sensitization, lung function parameters, and the total IgE and eosinophil levels.

resultsOut of 365 allergic rhinitis patients (age range 16-64 years), 114 showed BHR. Sensitization to house dust mites (HDMs) and grass were the most common. BHR was significantly associated with sensitization to dogs (odds ratio, OR = 2.15, 95% confidence interval, CI: 1.13-4.11) and Alternaria (OR = 2.15, 95% CI: 1.06-4.35); however, BHR did not show a relationship with HDMs sensitization. The levels of total IgE and eosinophils were higher in the BHR-positive group. Sensitization to more than six allergens significantly increased the probability of BHR (p < 0.01).

conclusionDogs and Alternaria, but not HDMs, were the sensitizing agents most closely associated with BHR. High-grade sensitization and increased total IgE and eosinophil levels were characteristic clinical signs in BHR-positive allergic rhinitis patients in the temperate continental climatic zone.

Indexed as

Bronchial HyperreactivityRhinitis, AllergicAdolescentAdultAllergensAnimalsBiomarkersClimateDogsHumansImmunoglobulin EMiddle AgedRetrospective StudiesYoung AdultAllergensBiomarkersImmunoglobulin EAlternariaAsthmaBronchial provocation testHouse dust mitesPets

Identifiers

PMID36074179
OpenAlexW4294955722

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.