Evidence map›Paper›PMID 36074159›Full record

ArticleCancer immunology, immunotherapy : CII2023

Anti-PD-1 antibody-activated Th17 cells subvert re-invigoration of antitumor cytotoxic T-lymphocytes via myeloid cell-derived COX-2/PGE

Qingsheng Li, Kevin E Goggin, SeonYeong Seo, Jonathan M Warawa, Nejat K Egilmez

Erratum issuedOpen access · greenAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Cancer immunology, immunotherapy : CII, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. An erratum has been issued. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
0.5field-weighted citation impact, top 33% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed, 5 citations in OpenAlex.

  1. Adaptive resistance in cancer immunotherapy.Cellular & molecular immunology · 2026
    Review
  2. Article
  3. Review
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  5. Review
4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

5 authors at 1 institution in 1 country.

Qingsheng LiDepartment of Microbiology and Immunology, School of Medicine, University of Louisville, 505 S.Hancock St, Louisville, KY, 40202, USA. qingsheng.li@louisville.edu.
Kevin E GogginDepartment of Microbiology and Immunology, School of Medicine, University of Louisville, 505 S.Hancock St, Louisville, KY, 40202, USA.
SeonYeong SeoDepartment of Microbiology and Immunology, School of Medicine, University of Louisville, 505 S.Hancock St, Louisville, KY, 40202, USA.
Jonathan M WarawaDepartment of Microbiology and Immunology, School of Medicine, University of Louisville, 505 S.Hancock St, Louisville, KY, 40202, USA.
Nejat K EgilmezDepartment of Microbiology and Immunology, School of Medicine, University of Louisville, 505 S.Hancock St, Louisville, KY, 40202, USA. nejat.egilmez@louisville.edu.
University of Louisville · US

Funding

The role of ECM-mediated mechanosignaling on regional immunosuppression in GBMP20GM135004 · NIGMS · UNIVERSITY OF LOUISVILLE · PI Sharmila Nair · 2020 to 2026
$21.1M
Congressionally Directed Medical Research Programs W81XWH1910265NIGMS NIH HHS P20 GM135004NIGMS NIH HHS P20-GM135004
6 · The paper itself

Abstract

Anti-PD-1 antibody-mediated activation of type 17 T-cells undermines checkpoint inhibitor therapy in the LSL-Kras

Indexed as

Th17 CellsT-Lymphocytes, CytotoxicAnimalsCyclooxygenase 2DinoprostoneInterleukin-17MiceMyeloid CellsProto-Oncogene Proteins p21(ras)Cyclooxygenase 2DinoprostoneInterleukin-17Proto-Oncogene Proteins p21(ras)Anti-PD-1 resistanceCOX-2Lung microbiotaNSCLCPGE2Th17 cell

Identifiers

PMID36074159
PMCPMC9992446
OpenAlexW4294991171

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.