Evidence map›Paper›PMID 36073960›Full record

ArticleMicrobiology spectrum2022

The Two-Component System CpxRA Represses Salmonella Pathogenicity Island 2 by Directly Acting on the

Nancy León-Montes, Jessica Nava-Galeana, Diana Rodríguez-Valverde, Jorge Soria-Bustos, Roberto Rosales-Reyes, Sandra Rivera-Gutiérrez, Hidetada Hirakawa, Miguel A Ares, Víctor H Bustamante, Miguel A De la Cruz

Open access · goldAbstract read
In one paragraph

Article in Microbiology spectrum, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers.

0numbers the graph read from it
0cells of the map it votes in
7citing papers in PubMed
1.2field-weighted citation impact, top 22% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

7 citing papers in PubMed, 8 citations in OpenAlex.

  1. The divergentMicrobiology (Reading, England) · 2026
    Article
  2. Review
  3. Anti-infective compounds forSustainable microbiology · 2026
    Review
  4. Article
  5. Article
  6. Review
  7. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors at 4 institutions in 2 countries.

Nancy León-MontesUnidad de Investigación Médica en Enfermedades Infecciosas y Parasitarias, Hospital de Pediatría, Centro Médico Nacional Siglo XXI, Instituto Mexicano del Seguro Social, Mexico City, Mexico.
Jessica Nava-GaleanaDepartamento de Microbiología Molecular, Instituto de Biotecnología, Universidad Nacional Autónoma de México, Cuernavaca, Mexico.
Diana Rodríguez-ValverdeUnidad de Investigación Médica en Enfermedades Infecciosas y Parasitarias, Hospital de Pediatría, Centro Médico Nacional Siglo XXI, Instituto Mexicano del Seguro Social, Mexico City, Mexico.
Jorge Soria-BustosUnidad de Investigación Médica en Enfermedades Infecciosas y Parasitarias, Hospital de Pediatría, Centro Médico Nacional Siglo XXI, Instituto Mexicano del Seguro Social, Mexico City, Mexico.
Roberto Rosales-ReyesUnidad de Medicina Experimental, Facultad de Medicina, Universidad Nacional Autónoma de México, Mexico City, Mexico.ORCID 0000-0001-9519-8766
Sandra Rivera-GutiérrezDepartamento de Microbiología, Escuela Nacional de Ciencias Biológicas, Instituto Politécnico Nacionalgrid.418275.d, Mexico City, Mexico.
Hidetada HirakawaDepartment of Bacteriology, Gunma University Graduate School of Medicine, Maebashi, Japan.ORCID 0000-0002-9528-4012
Miguel A AresUnidad de Investigación Médica en Enfermedades Infecciosas y Parasitarias, Hospital de Pediatría, Centro Médico Nacional Siglo XXI, Instituto Mexicano del Seguro Social, Mexico City, Mexico.
Víctor H BustamanteDepartamento de Microbiología Molecular, Instituto de Biotecnología, Universidad Nacional Autónoma de México, Cuernavaca, Mexico.
Miguel A De la CruzUnidad de Investigación Médica en Enfermedades Infecciosas y Parasitarias, Hospital de Pediatría, Centro Médico Nacional Siglo XXI, Instituto Mexicano del Seguro Social, Mexico City, Mexico.
Mexican Social Security Institute · MXUniversidad Nacional Autónoma de México · MXGunma University · JPInstituto Politécnico Nacional · MX

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The acquisition of Salmonella pathogenicity island 2 (SPI-2) conferred on Salmonella the ability to survive and replicate within host cells. The

Indexed as

Gene Expression Regulation, BacterialGenomic IslandsAnimalsBacterial ProteinsMiceOperonSalmonella typhimuriumTranscription FactorsType III Secretion SystemsBacterial ProteinsTranscription FactorsType III Secretion SystemscpxRACpxRASalmonellaSPI-2ssrAB

Identifiers

PMID36073960
PMCPMC9603713
OpenAlexW4294992068

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.