Evidence map›Paper›PMID 36073931›Full record

ArticleMicrobiology spectrum2022

Mechanisms of IS

Christopher J Harmer, Francois Lebreton, Jason Stam, Patrick T McGann, Ruth M Hall

Open access · goldAbstract read
In one paragraph

Article in Microbiology spectrum, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 18 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
18citing papers in PubMed, 1 pooled it
1.9field-weighted citation impact, top 13% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

18 citing papers in PubMed, 1 synthesis or guideline pooled it, 27 citations in OpenAlex.

  1. Pooled it
  2. ISmLife · 2026
    Article
  3. Article
  4. Review
  5. Article
  6. Article
  7. Article
  8. ISiScience · 2025
    Article
  9. Article
  10. ISMicrobiology and molecular biology reviews : MMBR · 2024
    Review
  11. Article
  12. Article
  13. Article
  14. Article
  15. Article
  16. Article
  17. Article
  18. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 2 institutions in 2 countries.

Christopher J HarmerSchool of Life and Environmental Sciences, The University of Sydneygrid.1013.3, Sydney, New South Wales, Australia.ORCID 0000-0003-1486-454X
Francois LebretonMultidrug Resistant Organism Repository and Surveillance Network, Walter Reed Army Institute of Research, Silver Spring, Maryland, USA.ORCID 0000-0002-7157-5026
Jason StamMultidrug Resistant Organism Repository and Surveillance Network, Walter Reed Army Institute of Research, Silver Spring, Maryland, USA.
Patrick T McGannMultidrug Resistant Organism Repository and Surveillance Network, Walter Reed Army Institute of Research, Silver Spring, Maryland, USA.
Ruth M HallSchool of Life and Environmental Sciences, The University of Sydneygrid.1013.3, Sydney, New South Wales, Australia.ORCID 0000-0003-2062-3312
Walter Reed Army Institute of Research · USThe University of Sydney · AU

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Enhanced levels of resistance to antibiotics arising from amplification of an antibiotic resistance gene that impact therapeutic options are increasingly observed. Amplification can also disclose novel phenotypes leading to treatment failure. However, the mechanism is poorly understood. Here, the route to amplification of the

Indexed as

Acinetobacter baumanniiAnti-Bacterial AgentsDNA Transposable ElementsDrug Resistance, BacterialNeomycinTobramycinAnti-Bacterial AgentsDNA Transposable ElementsNeomycinTobramycinantibiotic resistancegene amplificationheteroresistanceIS26tobramycin resistance

Identifiers

PMID36073931
PMCPMC9602291
OpenAlexW4294991760

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.