Evidence map›Paper›PMID 36073733›Full record

ArticleEpigenetics2022

Dominant effects of the histone mutant H3-L61R on Spt16-gene interactions in budding yeast.

Alex Pablo-Kaiser, McKenzie G Tucker, Grace A Turner, Elijah G Dilday, Avery G Olmstead, Caroline L Tackett, Andrea A Duina

Open access · hybridAbstract read
In one paragraph

Article in Epigenetics, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
0.3field-weighted citation impact, top 48% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed, 3 citations in OpenAlex.

  1. Review
  2. Article
  3. Article
  4. Review
  5. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 1 institution in 1 country.

Alex Pablo-KaiserBiology and Health Sciences Department, Hendrix College, Conway, Arkansas, USA.
McKenzie G TuckerBiology and Health Sciences Department, Hendrix College, Conway, Arkansas, USA.
Grace A TurnerBiology and Health Sciences Department, Hendrix College, Conway, Arkansas, USA.
Elijah G DildayBiology and Health Sciences Department, Hendrix College, Conway, Arkansas, USA.
Avery G OlmsteadBiology and Health Sciences Department, Hendrix College, Conway, Arkansas, USA.
Caroline L TackettBiology and Health Sciences Department, Hendrix College, Conway, Arkansas, USA.
Andrea A DuinaBiology and Health Sciences Department, Hendrix College, Conway, Arkansas, USA.ORCID 0000-0002-6040-6825
Hendrix College · US

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Recent studies have unveiled an association between an L61R substitution within the human histone H3.3 protein and the presentation of neurodevelopmental disorders in two patients. In both cases, the mutation responsible for this substitution is encoded by one allele of the

Indexed as

Saccharomyces cerevisiae ProteinsSaccharomycetalesDNA MethylationHistonesHumansMutationNucleosomesSaccharomyces cerevisiaeTranscriptional Elongation FactorsHistonesNucleosomesSaccharomyces cerevisiae ProteinsTranscriptional Elongation FactorschromatinFACT complexHistone H3histone H3.3nucleosomesSpt16yeast

Identifiers

PMID36073733
PMCPMC9665134
OpenAlexW4294991858

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.