Evidence map›Paper›PMID 36073708›Full record

ArticleWorld psychiatry : official journal of the World Psychiatric Association (WPA)2022

Adverse childhood experiences and mental health problems in a nationally representative study of heterosexual, homosexual and bisexual Danes.

Josefine Bernhard Andresen, Christian Graugaard, Mikael Andersson, Mikkel Kjaer Bahnsen, Morten Frisch

Open access · greenAbstract read
In one paragraph

Article in World psychiatry : official journal of the World Psychiatric Association (WPA), 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 20 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
20citing papers in PubMed, 1 pooled it
7.8field-weighted citation impact, top 2% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

20 citing papers in PubMed, 1 synthesis or guideline pooled it, 40 citations in OpenAlex.

  1. Pooled it
  2. Article
  3. Early life stress modulates social behavior via oxytocin and arginine vasopressin in males.European archives of psychiatry and clinical neuroscience · 2026
    Article
  4. Article
  5. Article
  6. Article
  7. Sexual identity, child maltreatment, mental health, and substance use among emerging adults aged 18 to 23 years.Canadian journal of public health = Revue canadienne de sante publique · 2025
    Article
  8. Article
  9. Article
  10. Article
  11. Observational
  12. Article
  13. Article
  14. Article
  15. Article
  16. Adverse childhood experiences: a meta-analysis of prevalence and moderators among half a million adults in 206 studies.World psychiatry : official journal of the World Psychiatric Association (WPA) · 2023
    Article
  17. Review
  18. Review
  19. Article
  20. Childhood gender non-conformity, sexual orientation and mental health problems among 18 to 89 year-old Danes.World psychiatry : official journal of the World Psychiatric Association (WPA) · 2023
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 2 institutions in 1 country.

Josefine Bernhard AndresenDepartment of Epidemiology Research, Statens Serum Institut, Copenhagen, Denmark.
Christian GraugaardDepartment of Clinical Medicine, Center for Sexology Research, Aalborg University, Aalborg, Denmark.
Mikael AnderssonDepartment of Epidemiology Research, Statens Serum Institut, Copenhagen, Denmark.
Mikkel Kjaer BahnsenDepartment of Epidemiology Research, Statens Serum Institut, Copenhagen, Denmark.
Morten FrischDepartment of Epidemiology Research, Statens Serum Institut, Copenhagen, Denmark.
Statens Serum Institut · DKAalborg University · DK

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Non-heterosexual persons more often report adverse childhood experiences (ACEs) than heterosexuals, and they generally bear a greater burden of mental health challenges. However, population-based data on this topic are scarce. In a nationally representative study within the Project SEXUS, one of the world's largest cohort studies on sexual health, we used data from 57,479 individuals in Denmark to explore the interplay between ACEs and mental health problems among self-identified heterosexual, homosexual and bisexual persons, and among self-identified heterosexuals with or without same-sex sexual experience. Compared to heterosexuals, non-heterosexual persons were more likely to report most of the studied ACEs, with odds ratios (ORs) for the ACE category "abuse" ranging from 1.38 to 1.75 for homosexual women, from 1.76 to 2.65 for homosexual men, from 2.52 to 3.64 for bisexual women, and from 1.58 to 6.07 for bisexual men. Furthermore, non-heterosexual persons had consistently and statistically significantly higher odds for mental health problems (ORs: 1.50 to 4.63). Combinations of ACEs with a non-heterosexual identity resulted in markedly elevated odds for mental health problems, particularly among bisexual individuals. This included high odds for suicidal thoughts/attempts among bisexual persons with a history of "neglect" (women: OR=12.82; men: OR=35.24) and "abuse" (women: OR=11.81; men: OR=11.65). Among self-identified heterosexuals, combinations of ACEs with same-sex sexual experience were associated with consistently elevated odds for mental health problems (ORs: 2.22 to 12.04). The greater burden of ACEs among self-identified homosexuals and, most notably, bisexuals may account for part of their excess risk of mental health problems. These findings emphasize the public health importance of preventive measures to minimize the burden of ACEs and avert their harmful long-term effects. Moreover, they highlight the need to safeguard the welfare of children and adolescents with non-conforming expressions of sexuality.

Indexed as

adverse childhood experiencesbisexualityheterosexualityHomosexualitymental healthself-harmsuicidality

Identifiers

PMID36073708
PMCPMC9453895
OpenAlexW4294992296

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.