Article in Journal of the American Heart Association, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.
0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed
2.2field-weighted citation impact, top 12% of its field
1 · What the graph read from it
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
2 · The registry
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
3 · Its place in the literature
Who cites it
6 citing papers in PubMed, 8 citations in OpenAlex.
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
5 · Who and what money
Authors and funding
17 authors at 9 institutions in 1 country.
Ravi V ShahVanderbilt Translational and Clinical Research Center Cardiology Division Vanderbilt University Medical Center Nashville TN.ORCID 0000-0002-4471-7156
Patricia MillerDepartment of Biostatistics Boston University School of Public Health Boston MA.
Laura A ColangeloDepartment of Preventive Medicine Feinberg School of Medicine Northwestern University Chicago IL.ORCID 0000-0001-9322-705X
Ariel ChernofskyDepartment of Biostatistics Boston University School of Public Health Boston MA.ORCID 0000-0002-7104-409X
Nicholas E HoustisCardiology Division Department of Medicine Massachusetts General Hospital Harvard Medical School Boston MA.
Rajeev MalhotraCardiology Division Department of Medicine Massachusetts General Hospital Harvard Medical School Boston MA.ORCID 0000-0003-0120-4630
Raghava S VelagaletiCardiology Section Department of Medicine Boston VA Healthcare System West Roxbury MA.ORCID 0000-0002-2725-2692
David R JacobsDivision of Epidemiology and Community Health School of Public Health University of Minnesota Minneapolis MN.ORCID 0000-0002-7232-0543
Kelley Pettee GabrielDepartment of Epidemiology University of Alabama at Birmingham Birmingham AL.ORCID 0000-0003-4986-7927
Jared P ReisDivision of Cardiovascular Sciences, National Heart, Lung, and Blood Institute Bethesda MD.
Donald M Lloyd-JonesDepartment of Preventive Medicine Feinberg School of Medicine Northwestern University Chicago IL.ORCID 0000-0003-0847-6110
Martin G LarsonDepartment of Biostatistics Boston University School of Public Health Boston MA.ORCID 0000-0002-9631-1254
Ramachandran S VasanBoston University's and National Heart, Lung, and Blood Institute's Framingham Heart Study Framingham MA.ORCID 0000-0001-7357-5970
Venkatesh L MurthyDepartment of Epidemiology Boston University School of Public Health, and the Center for Computing and Data Sciences Boston University Boston MA.ORCID 0000-0002-7901-1321
Gregory D LewisCardiology Division Department of Medicine Massachusetts General Hospital Harvard Medical School Boston MA.ORCID 0000-0001-8108-8240
Matthew NayorSections of Cardiovascular Medicine and Preventive Medicine and Epidemiology Department of Medicine Boston University School of Medicine Boston MA.ORCID 0000-0002-6993-9396
Boston University · USHarvard University · USNorthwestern University · USBroad Institute · USNational Heart Lung and Blood Institute · USUniversity of Alabama at Birmingham · USUniversity of Minnesota · USVA Boston Healthcare System · USVanderbilt University Medical Center · US
Funding
THE FRAMINGHAM HEART STUDYN01HC25195 · NHLBI · BOSTON UNIVERSITY MEDICAL CAMPUS · PI RAMACHANDRAN, VASAN S · 2007 to 2014
$83.8M
FRAMINGHAM HEART STUDY - YEAR 5 EXAM75N92019D00031 · NHLBI · BOSTON UNIVERSITY MEDICAL CAMPUS · PI RAMACHANDRAN, VASAN · 2019 to 2024
$29.8M
Proteomic Profiling of Precise Exercise Pathophenotypes Across the HFpEF SpectrumR01HL131029 · NHLBI · MASSACHUSETTS GENERAL HOSPITAL · PI Gregory Dyer Lewis, Matthew G. Nayor · 2016 to 2026
$7.7M
20 YEAR CHANGES IN FITNESS &CARDIOVASCULAR DISEASE RISKR01HL078972 · NHLBI · KAISER FOUNDATION RESEARCH INSTITUTE · PI SIDNEY, STEPHEN · 2005 to 2008
$6.1M
Young Adult and Midlife Transitions in Physical Activity and Sedentary Behavior with Heart Failure Risk and Progression: Coronary Artery Risk Development in Young Adults (CARDIA)R01HL149796 · NHLBI · UNIVERSITY OF ALABAMA AT BIRMINGHAM · PI GABRIEL, KELLEY PETTEE · 2020 to 2023
$5.6M
The Role of Histone Deacetylase 9 in Vascular CalcificationR01HL142809 · NHLBI · MASSACHUSETTS GENERAL HOSPITAL · PI MALHOTRA, RAJEEV · 2018 to 2022
$4.0M
Metabolic Responses to an Oral Mixed Meal Tolerance Test: Intra-individual changes, correlates, and prognostic significanceR01HL156975 · NHLBI · BOSTON UNIVERSITY MEDICAL CAMPUS · PI NAYOR, MATTHEW G. · 2021 to 2025
$3.3M
Molecular markers of early cardiometabolic health transitions in the CARDIA studyR01HL136685 · NHLBI · UNIVERSITY OF MICHIGAN AT ANN ARBOR · PI MURTHY, VENKATESH LOCHARLA, SHAH, RAVI · 2017 to 2021
$2.6M
Characterization of Functional Iron Deficiency and Repletion in Heart Failure with Preserved Ejection FractionR01HL159514 · NHLBI · MASSACHUSETTS GENERAL HOSPITAL · PI LEWIS, GREGORY DYER, MALHOTRA, RAJEEV · 2021 to 2024
$2.5M
Metabolic Signatures of Impaired Cardiorespiratory Fitness: Correlates, Prognostic Significance and Modulation with Exercise TrainingK23HL138260 · NHLBI · MASSACHUSETTS GENERAL HOSPITAL · PI NAYOR, MATTHEW G. · 2017 to 2021
Background Cardiorespiratory fitness is a powerful predictor of health outcomes that is currently underused in primary prevention, especially in young adults. We sought to develop a blood-based biomarker of cardiorespiratory fitness that is easily translatable across populations. Methods and Results Maximal effort cardiopulmonary exercise testing for quantification of cardiorespiratory fitness (by peak oxygen uptake) and profiling of >200 metabolites at rest were performed in the FHS (Framingham Heart Study; 2016-2019). A metabolomic fitness score was derived/validated in the FHS and was associated with long-term outcomes in the younger CARDIA (Coronary Artery Risk Development in Young Adults) study. In the FHS (derivation, N=451; validation, N=914; age 54±8 years, 53% women, body mass index 27.7±5.3 kg/m
Indexed as
Cardiorespiratory FitnessCardiovascular DiseasesAdultBiomarkersExercise TestFemaleHumansMaleMiddle AgedOutcome Assessment, Health CareOxygenPhysical FitnessRisk FactorsYoung AdultBiomarkersOxygenbody mass indexcardiorespiratory fitnessexercise testlinear modelslongitudinal studies
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.
Blood-Based Fingerprint of Cardiorespiratory Fitness and Long-Term Health Outcomes in Young Adulthood. · full record | OpenQuestion