Evidence map›Paper›PMID 36073628›Full record

ArticleJournal of the American Heart Association2022

Differential Patterns and Outcomes of 20.6 Million Cardiovascular Emergency Department Encounters for Men and Women in the United States.

Zahra Raisi-Estabragh, Ofer Kobo, Ayman Elbadawi, Poonam Velagapudi, Garima Sharma, Renee P Bullock-Palmer, Steffen E Petersen, Laxmi S Mehta, Waqas Ullah, Ariel Roguin and 2 more

Open access · goldAbstract read
In one paragraph

Article in Journal of the American Heart Association, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 16 papers.

0numbers the graph read from it
0cells of the map it votes in
16citing papers in PubMed
3.8field-weighted citation impact, top 5% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

16 citing papers in PubMed, 25 citations in OpenAlex.

  1. Trial
  2. Observational
  3. Assessment of adherence to acute pulmonary embolism management guidelines: a single-centre registry.The Egyptian heart journal : (EHJ) : official bulletin of the Egyptian Society of Cardiology · 2026
    Article
  4. Observational
  5. Article
  6. A Blueprint for Building a Renal Denervation Program.Journal of the Society for Cardiovascular Angiography & Interventions · 2025
    Review
  7. Article
  8. Article
  9. Review
  10. Article
  11. A closer look at gender disparities in patients with pulmonary embolism.Proceedings (Baylor University. Medical Center) · 2025
    Article
  12. Article
  13. Review
  14. Review
  15. Article
  16. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors at 10 institutions in 4 countries.

Zahra Raisi-EstabraghNational Institute for Heart Research Barts Biomedical Research Centre, Centre for Advanced Cardiovascular Imaging William Harvey Research Institute, Queen Mary University London London United Kingdom.ORCID 0000-0002-7757-5465
Ofer KoboKeele Cardiovascular Research Group Keele University Keele United Kingdom.
Ayman ElbadawiDepartment of Cardiovascular Medicine and Division of Cardiology, Baylor College of Medicine Houston TX.ORCID 0000-0002-4248-781X
Poonam VelagapudiUniversity of Nebraska Medical Center Omaha NE.
Garima SharmaDivision of Cardiology, Johns Hopkins Ciccarone Center for Prevention of Cardiovascular Disease Johns Hopkins University School of Medicine and Hospital Baltimore MD.ORCID 0000-0001-7254-2077
Renee P Bullock-PalmerDepartment of Cardiology Deborah Heart and Lung Center Brown Mills NJ.
Steffen E PetersenNational Institute for Heart Research Barts Biomedical Research Centre, Centre for Advanced Cardiovascular Imaging William Harvey Research Institute, Queen Mary University London London United Kingdom.ORCID 0000-0003-4622-5160
Laxmi S MehtaDivision of Cardiology, Department of Internal Medicine The Ohio State University Columbus OH.ORCID 0000-0003-3493-1930
Waqas UllahThomas Jefferson University Hospitals Philadelphia PA.ORCID 0000-0002-4850-0309
Ariel RoguinDepartment of Cardiology Hillel Yaffe Medical Center Hadera Israel.
Louise Y SunDivision of Cardiac Anesthesiology University of Ottawa Heart Institute Ottawa Ontario Canada.ORCID 0000-0003-3381-3115
Mamas A MamasKeele Cardiovascular Research Group Keele University Keele United Kingdom.ORCID 0000-0001-9241-8890
Hillel Yaffe Medical Center · ILNational Health Service · GBBaylor College of Medicine · USDeborah Heart and Lung Center · USJohns Hopkins University · USThe Ohio State University · USThomas Jefferson University Hospital · USUniversity of Manchester · GBUniversity of Nebraska Medical Center · USUniversity of Ottawa · CA

Funding

British Heart Foundation FS/17/81/33318Department of Health
6 · The paper itself

Abstract

Background We describe sex-differential disease patterns and outcomes of >20.6 million cardiovascular emergency department encounters in the United States. Methods and Results We analyzed primary cardiovascular encounters from the Nationwide Emergency Department Sample between 2016 and 2018. We grouped cardiovascular diagnoses into 15 disease categories. The sample included 48.7% women; median age was 67 (interquartile range, 54-78) years. Men had greater overall baseline comorbidity burden; however, women had higher rates of obesity, hypertension, and cerebrovascular disease. For women, the most common emergency department encounters were essential hypertension (16.0%), hypertensive heart or kidney disease (14.1%), and atrial fibrillation/flutter (10.2%). For men, the most common encounters were hypertensive heart or kidney disease (14.7%), essential hypertension (10.8%), and acute myocardial infarction (10.7%). Women were more likely to present with essential hypertension, hypertensive crisis, atrial fibrillation/flutter, supraventricular tachycardia, pulmonary embolism, or ischemic stroke. Men were more likely to present with acute myocardial infarction or cardiac arrest. In logistic regression models adjusted for baseline covariates, compared with men, women with intracranial hemorrhage had higher risk of hospitalization and death. Women presenting with pulmonary embolism or deep vein thrombosis were less likely to be hospitalized. Women with aortic aneurysm/dissection had higher odds of hospitalization and death. Men were more likely to die following presentations with hypertensive heart or kidney disease, atrial fibrillation/flutter, acute myocardial infarction, or cardiac arrest. Conclusions In this large nationally representative sample of cardiovascular emergency department presentations, we demonstrate significant sex differences in disease distribution, hospitalization, and death.

Indexed as

Atrial FibrillationAtrial FlutterHeart ArrestHypertensionMyocardial InfarctionPulmonary EmbolismAgedEmergency Service, HospitalEssential HypertensionFemaleHumansMaleRisk FactorsUnited Statesatrial fibrillationessential hypertensionmensex characteristicsstrokeUnited Stateswomen

Identifiers

PMID36073628
PMCPMC9673731
OpenAlexW4294990922

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.