Evidence map›Paper›PMID 36073323›Full record

ReviewJournal of magnetic resonance imaging : JMRI2023

Rectal MRI Interpretation After Neoadjuvant Therapy.

Natally Horvat, Maria El Homsi, Joao Miranda, Yousef Mazaheri, Marc J Gollub, Viktoriya Paroder

Abstract readReview
In one paragraph

Review in Journal of magnetic resonance imaging : JMRI, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 24 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
24citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

24 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Pooled it
  2. Article
  3. Article
  4. Article
  5. Article
  6. Article
  7. Article
  8. Article
  9. Review
  10. Article
  11. Article
  12. Article
  13. MRI for Rectal Cancer: Updates and Controversies-AJR. American journal of roentgenology · 2025
    Review
  14. Review
  15. Article
  16. Article
  17. Review
  18. Article
  19. Nonoperative management of rectal cancer.Frontiers in oncology · 2024
    Review
  20. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Natally HorvatDepartment of Radiology, Memorial Sloan Kettering Cancer Center, New York, New York, USA.
Maria El HomsiDepartment of Radiology, Memorial Sloan Kettering Cancer Center, New York, New York, USA.
Joao MirandaDepartment of Radiology, University of Sao Paulo, Sao Paulo, Brazil.
Yousef MazaheriDepartment of Medical Physics, Memorial Sloan Kettering Cancer Center, New York, New York, USA.
Marc J GollubDepartment of Radiology, Memorial Sloan Kettering Cancer Center, New York, New York, USA.ORCID 0000-0002-6008-0730
Viktoriya ParoderDepartment of Radiology, Memorial Sloan Kettering Cancer Center, New York, New York, USA.

Funding

X-RAY CRYSTALLOGRAPHYP30CA008748 · NCI · SLOAN-KETTERING INSTITUTE FOR CANCER RES · PI Hongbiao Carl Lekaye · 1985 to 2026
$347.4M
NCI NIH HHS P30 CA008748
6 · The paper itself

Abstract

In recent years, several key advances in the management of locally advanced rectal cancer have been made, including the implementation of total mesorectal excision as the standard surgical approach; use of neoadjuvant chemoradiotherapy in selected patients with a high risk of local recurrence, and finally, adoption of organ preservation strategies, through either local excision or nonoperative management in selected patients with clinical complete response following neoadjuvant chemoradiotherapy. This review aims to shed light on the role of rectal MRI in the assessment of treatment response after neoadjuvant therapy, which is especially important given the growing feasibility of nonoperative management. First, an overview of current neoadjuvant therapies and response assessment based on digital rectal examination, endoscopy, and MRI will be provided. Second, the use of a high-quality restaging rectal MRI protocol will be presented. Third, a step-by-step approach to assessing treatment response on restaging rectal MRI following neoadjuvant treatment will be outlined, acknowledging challenges faced by radiologists during MRI interpretation. Finally, research related to response assessment will be discussed. LEVEL OF EVIDENCE: 4 TECHNICAL EFFICACY: Stage 3.

Indexed as

Neoadjuvant TherapyRectal NeoplasmsChemoradiotherapyHumansMagnetic Resonance ImagingNeoplasm Recurrence, LocalNeoplasm StagingRectumTreatment Outcomemagnetic resonance imagingneoadjuvant therapyrectal cancer

Identifiers

PMID36073323
PMCPMC9851947

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.