Evidence map›Paper›PMID 36073246›Full record

SynthesisAnatomia, histologia, embryologia2022

Anatomy, histology, development and functions of Ossa cordis: A review.

Adam Best, Monika Egerbacher, Sophia Swaine, William Pérez, Aziza Alibhai, Paul Rutland, Valentina Kubale, Samir A A El-Gendy, Mohamed A M Alsafy, Kerstin Baiker and 2 more

Open access · hybridAbstract readSystematic Review
In one paragraph

Synthesis in Anatomia, histologia, embryologia, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
8citing papers in PubMed, 2 pooled it
1.9field-weighted citation impact, top 14% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

8 citing papers in PubMed, 2 syntheses or guidelines pooled it, 22 citations in OpenAlex.

  1. Pooled it
  2. Pooled it
  3. Cardiac morphology of Phalacrocorax brasilianus.Anatomical record (Hoboken, N.J. : 2007) · 2026
    Article
  4. Large animal models of right heart failure due to pulmonary hypertension: a bridge to translational success.European respiratory review : an official journal of the European Respiratory Society · 2026
    Review
  5. Article
  6. Article
  7. Article
  8. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors at 6 institutions in 5 countries.

Adam BestSchool of Veterinary Medicine and Science, Faculty of Medicine and Health Science, University of Nottingham, Leicestershire, UK.
Monika EgerbacherAdmin. Unit of Veterinary Medicine, UMIT TIROL - Private University for Health Sciences, Medical Informatics and Technology, Hall in Tirol, Tyrol, Austria.
Sophia SwaineSchool of Veterinary Medicine and Science, Faculty of Medicine and Health Science, University of Nottingham, Leicestershire, UK.
William PérezUnidad de Anatomía, Facultad de Veterinaria, Universidad de la República, Montevideo, Uruguay.ORCID https://orcid.org/0000-0002-9647-4731
Aziza AlibhaiSchool of Veterinary Medicine and Science, Faculty of Medicine and Health Science, University of Nottingham, Leicestershire, UK.
Paul RutlandUniversity College London, Great Ormond Street Institute of Child Health, London, UK.
Valentina KubaleVeterinary Faculty, Institute of Preclinical Sciences, University of Ljubljana, Ljubjana, Slovenia.
Samir A A El-GendyDepartment of Anatomy and Embryology, Faculty of Veterinary Medicine, Alexandria University, Egypt.ORCID https://orcid.org/0000-0002-6180-389X
Mohamed A M AlsafyDepartment of Anatomy and Embryology, Faculty of Veterinary Medicine, Alexandria University, Egypt.ORCID https://orcid.org/0000-0001-6236-4801
Kerstin BaikerSchool of Veterinary Medicine and Science, Faculty of Medicine and Health Science, University of Nottingham, Leicestershire, UK.
Craig J SturrockThe Hounsfield Facility, School of Biosciences, University of Nottingham, Leicestershire, UK.ORCID https://orcid.org/0000-0002-5333-8502
Catrin Sian RutlandSchool of Veterinary Medicine and Science, Faculty of Medicine and Health Science, University of Nottingham, Leicestershire, UK.ORCID https://orcid.org/0000-0002-2009-4898
University of Nottingham · GBAlexandria University · EGGreat Ormond Street Hospital · GBUMIT - Private Universität für Gesundheitswissenschaften, Medizinische Informatik und Technik · ATUniversidad de la República de Uruguay · UYUniversity of Ljubljana · SI

Funding

Biotechnology and Biological Sciences Research CouncilEuropean Research Council
6 · The paper itself

Abstract

This systematic review highlights the similarities and variations in Ossa cordis prevalence, histology and anatomical location between differing veterinary species and in humans. In addition, it also identifies associated factors such as aging and cardiovascular disease for each species in relation to functional roles and developmental mechanisms that these bone structures may play. The potential functions of Ossa cordis are presented, ranging from aiding cardiac contraction and conduction, providing cardiac structure, and protecting components of the heart, through to counteracting high mechanical stress. Furthermore, this review discusses the evidence and rationale behind the theories regarding the formation and development of Ossa cordis in different veterinary species and in people.

Indexed as

Cardiovascular DiseasesHeartAnimalsBone and BonesHumansbonecardiacCartilago cordisectopic boneOssa cordisossification

Identifiers

PMID36073246
PMCPMC9826330
OpenAlexW4294992509

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.