Evidence map›Paper›PMID 36073018›Full record

ArticleCatheterization and cardiovascular interventions : official journal of the Society for Cardiac Angiography & Interventions2022

Characteristics and outcomes of patients presenting with acute myocardial infarction and cardiogenic shock during COVID-19.

Michael J Ahlers, Pratyaksh K Srivastava, Mir B Basir, William W O'Neill, Michael Hacala, Kareem Ammar, Suzan Khalil, John Hollowed, Ali Nsair

Registry-linked trialOpen access · greenAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Catheterization and cardiovascular interventions : official journal of the Society for Cardiac Angiography & Interventions, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT05800951 (Can Escalation Reduce Acute Myocardial Infarction Mortality in Cardiogenic Shock), which is not on this map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
0.4field-weighted citation impact, top 36% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT05800951 active not recruitingnot on this map

Can Escalation Reduce Acute Myocardial Infarction Mortality in Cardiogenic Shock (CERAMICS Study)

Typeobservational_patient_registrySponsorHenry Ford Health SystemRan2022 to 2026Enrolled124ConditionsCardiogenic Shock, Acute Myocardial Infarction, STEMI - ST Elevation Myocardial Infarction, NSTEMI - Non-ST Segment Elevation MI
3 · Its place in the literature

Who cites it

2 citing papers in PubMed, 4 citations in OpenAlex.

  1. Article
  2. Characteristics and outcomes of patients presenting with acute myocardial infarction and cardiogenic shock during COVID-19.Catheterization and cardiovascular interventions : official journal of the Society for Cardiac Angiography & Interventions · 2022
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 3 institutions in 1 country.

Michael J AhlersDepartment of Medicine, Ronald Reagan-UCLA Medical Center, Los Angeles, California, USA.ORCID 0000-0002-0282-6266
Pratyaksh K SrivastavaDivision of Cardiology, Ronald Reagan-UCLA Medical Center, Los Angeles, California, USA.
Mir B BasirDivision of Cardiology, Henry Ford Hospital/Wayne State University, Detroit, Michigan, USA.ORCID 0000-0003-3486-6753
William W O'NeillDivision of Cardiology, Henry Ford Hospital/Wayne State University, Detroit, Michigan, USA.
Michael HacalaDivision of Cardiology, Henry Ford Hospital/Wayne State University, Detroit, Michigan, USA.
Kareem AmmarDivision of Undergraduate Studies, University of California, Berkeley, California, USA.
Suzan KhalilAhmanson-UCLA Cardiomyopathy Center, Ronald Reagan-UCLA Medical Center, Los Angeles, California, USA.
John HollowedDivision of Cardiology, Ronald Reagan-UCLA Medical Center, Los Angeles, California, USA.ORCID 0000-0003-0732-5281
Ali NsairDivision of Cardiology, Ronald Reagan-UCLA Medical Center, Los Angeles, California, USA.
Ronald Reagan UCLA Medical Center · USWayne State University · USUniversity of California, Berkeley · US

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

objectivesTo evaluate characteristics and outcomes of patients presenting with acute myocardial infarction and cardiogenic shock (AMICS) during the coronavirus disease 2019 (COVID-19) pandemic.

backgroundThe COVID-19 pandemic has created challenges in delivering acute cardiovascular care. Quality measures and outcomes of patients presenting with AMICS during COVID-19 in the United States have not been well described.

methodsWe identified 406 patients from the National Cardiogenic Shock Initiative (NCSI) with AMICS and divided them into those presenting before (N = 346, 5/9/2016-2/29/2020) and those presenting during the COVID-19 pandemic (N = 60, 3/1/2020-11/10/2020). We compared baseline clinical data, admission characteristics, and outcomes.

resultsThe median age of the cohort was 64 years, and 23.7% of the group was female. There were no significant differences in age, sex, and medical comorbidities between the two groups. Patients presenting during the pandemic were less likely to be Black compared to those presenting prior. Median door to balloon (90 vs. 88 min, p = 0.38), door to support (88 vs. 78 min, p = 0.13), and the onset of shock to support (74 vs. 62 min, p = 0.15) times were not significantly different between the two groups. Patients presented with ST-elevation myocardial infarction more often during the COVID-19 period (95.0% vs. 80.0%, p = 0.005). In adjusted logistic regression models, COVID-19 period did not significantly associate with survival to discharge (odds ratio [OR] 1.09, 95% confidence interval [CI] 0.54-2.19, p = 0.81) or with 1-month survival (OR 0.82, 95% CI 0.42-1.61, p = 0.56).

conclusionsCare of patients presenting with AMICS has remained robust among hospitals participating in the NCSI during the COVID-19 pandemic.

Indexed as

COVID-19Heart-Assist DevicesMyocardial InfarctionPercutaneous Coronary InterventionST Elevation Myocardial InfarctionFemaleHumansMiddle AgedPandemicsShock, CardiogenicTreatment OutcomeUnited Statesacute myocardial infarction/STEMIcoronary artery disease, interventionmechanical circulatory support, ECMO/IABP/tandem/Impellashock, cardiogenic

Identifiers

PMID36073018
PMCPMC9539126
OpenAlexW4294948540

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.