Evidence map›Paper›PMID 36072999›Full record

ArticleClinical cardiology2022

Prognosis of PCI in AMI setting in the elderly population: Outcomes from the multicenter prospective e-ULTIMASTER registry.

Majdi Saada, Ofer Kobo, Jawed Polad, Majdi Halabi, Alexander J J IJsselmuiden, Ángel Puentes, Jacques Monségu, David Austin, Ruslan K Baisebenov, Fabrizio Spanó and 2 more

Open access · goldAbstract readMulticenter Study
PubMed Full text at PMC Publisher
In one paragraph

Article in Clinical cardiology, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers.

0numbers the graph read from it
0cells of the map it votes in
8citing papers in PubMed
2.1field-weighted citation impact, top 11% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

8 citing papers in PubMed, 13 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors at 9 institutions in 6 countries.

Majdi SaadaDepartment of Cardiology, Hillel Yaffe Medical Center, Technion-Faculty of Medicine, Hadera, Israel.
Ofer KoboDepartment of Cardiology, Hillel Yaffe Medical Center, Technion-Faculty of Medicine, Hadera, Israel.
Jawed PoladDepartment of Cardiology, Jeroen Bosch Ziekenhuis, 's Hertogenbosch, The Netherlands.
Majdi HalabiDepartment of Cardiology, Ziv Hospital, Safed, Israel.
Alexander J J IJsselmuidenCardiology Department, Amphia Hospital Breda, Breda, The Netherlands.
Ángel PuentesDepartment of Cardiology, San Juan de Dios Hospital, Santiago, Chile.
Jacques MonséguDepartment of Cardiology, Groupe Hospitalier Mutualiste, Institut Cardiovasculaire, Grenoble, France.
David AustinDepartment of Cardiology, The James Cook University Hospital, Middlesbrough, UK.
Ruslan K BaisebenovDepartment of Cardiology, Regional Cardiology Center, Pavlodar, Kazakhstan.
Fabrizio SpanóDepartment of Cardiology, Meander Medical Center, Amersfoort, The Netherlands.
Ariel RoguinDepartment of Cardiology, Hillel Yaffe Medical Center, Technion-Faculty of Medicine, Hadera, Israel.ORCID http://orcid.org/0000-0003-4628-1840
e-ULTIMASTER Investigators
Hillel Yaffe Medical Center · ILAmphia Ziekenhuis · NLGroupe Hospitalier Mutualiste de Grenoble · FRHospital San Juan de Dios · CLInnovative University of Eurasia · KZJames Cook University Hospital · GBJeroen Bosch Ziekenhuis · NLMeander Medisch Centrum · NLRebecca Sieff Hospital · IL

Funding

Terumo Europe N.V.
6 · The paper itself

Abstract

backgroundElderly patients with ST-elevation myocardial infarction (STEMI) who undergo percutaneous coronary intervention (PCI) are usually excluded from major trials. HYOPTHESIS: This study sought to assess 1-year clinical outcomes following PCI with a drug-eluting stent in patients older than 80 years old with STEMI.

methodsThe large all-comer, multicontinental e-ULTIMASTER registry included 7507 patients with STEMI who underwent PCI using the Ultimaster stent. The primary clinical endpoint was 1-year target lesion failure, a composite of cardiac death (CD), target vessel-related myocardial infarction (TV-MI), or clinically driven target lesion revascularization (CD-TLR).

resultsThere were 457 (6.1%) patients in the elderly group (≥80 years old) that were compared to 7050 (93.9%) patients <80 years. The elderly patients included more female patients and had significantly more comorbidities and had more complex coronary anatomy. The primary endpoint occurred in 7.2% of the elderly, compared to 3.1% of the younger group (p < .001). All-cause mortality was significantly higher among the elderly group compared to the younger group (10.1% vs. 2.3%, p < .0001), as well as CD (6.1% vs. 1.6%, p < .0001), but not TV-MI (1.1% vs. 0.7%, p = .34) or CD-TLR (1.1% vs. 1.4%, p = .63).

conclusionElderly patients with STEMI presentation had a higher incidence of the composite endpoint than younger patients. All-cause and CD were higher for elderly patients compared to patients younger than 80 years old. However, there was no difference in the incidence of TV-MI or target lesion revascularizations. These findings suggest that PCI for STEMI in elderly patients is relatively safe.

Indexed as

Drug-Eluting StentsMyocardial InfarctionPercutaneous Coronary InterventionST Elevation Myocardial InfarctionAgedAged, 80 and overFemaleHumansPrognosisProspective StudiesRegistriesTreatment Outcomeagecoronary artery diseaseelderlymyocardial infarctionoutcomestent

Identifiers

PMID36072999
PMCPMC9748751
OpenAlexW4294992612

What OpenQuestion holds

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LicenceCC BY
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.