Evidence map›Paper›PMID 36072932›Full record

SynthesisFrontiers in endocrinology2022

Safety and efficacy of thermal ablation for cervical metastatic lymph nodes in papillary thyroid carcinoma: A systematic review and meta-analysis.

Wanqing Tang, Xiuyun Tang, Danni Jiang, Xiaojuan Zhang, Rongling Wang, Xiaoyan Niu, Yichen Zang, Mingzhu Zhang, Xinya Wang, Cheng Zhao

Open access · goldAbstract readMeta-AnalysisSystematic Review
In one paragraph

Synthesis in Frontiers in endocrinology, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed
2.0field-weighted citation impact, top 12% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed, 15 citations in OpenAlex.

  1. Article
  2. Article
  3. Percutaneous Ablation of Thyroid Cancer.Radiology. Imaging cancer · 2025
    Review
  4. Article
  5. Article
  6. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors at 3 institutions in 1 country.

Wanqing TangDepartment of Ultrasound, The Affiliated Hospital of Qingdao University, Qingdao, China.
Xiuyun TangDepartment of Ultrasound, Zibo Central Hospital, Zibo, China.
Danni JiangDepartment of Ultrasound, The Affiliated Hospital of Qingdao University, Qingdao, China.
Xiaojuan ZhangDepartment of Ultrasound, The Affiliated Hospital of Qingdao University, Qingdao, China.
Rongling WangDepartment of Ultrasound, The Affiliated Hospital of Qingdao University, Qingdao, China.
Xiaoyan NiuDepartment of Ultrasound, The Affiliated Hospital of Qingdao University, Qingdao, China.
Yichen ZangDepartment of Ultrasound, The Affiliated Hospital of Qingdao University, Qingdao, China.
Mingzhu ZhangDepartment of Ultrasound, The Affiliated Hospital of Qingdao University, Qingdao, China.
Xinya WangDepartment of Ultrasound, The Affiliated Hospital of Qingdao University, Qingdao, China.
Cheng ZhaoDepartment of Ultrasound, The Affiliated Hospital of Qingdao University, Qingdao, China.
Qingdao University · CNAffiliated Hospital of Qingdao University · CNCentral Hospital of Zibo · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Background: To evaluate the safety and efficacy of radiofrequency ablation (RFA), microwave ablation (MWA), and laser ablation (LA) for the treatment of cervical metastatic lymph nodes (CMLNs) of papillary thyroid carcinoma (PTC). Methods: The Pubmed, EMBASE, Web of Science, and Cochrane Library databases were searched for studies on the safety and efficacy of thermal ablations (RFA, MWA, and LA) for the treatment of CMLNs of PTC until March 30, 2022. A review of 334 potential papers identified 17 eligible papers including 312 patients. Fixed-effects model or random-effects model was used to evaluate the pooled proportions of volume reduction rate (VRR), complete disappearance, and recurrence, and pooled estimates of changes in the largest diameter, volume, and serum Results: 17 eligible studies were finally identified, including 312 patients and 559 CMLNs. The pooled proportions of VRR, complete disappearance and recurrence of CMLNs were 91.28% [95% confidence interval Conclusion: All thermal ablations were safe and effective for the treatment of CMLNs of PTC. However, each treatment had significant heterogeneity in VRR. Compared with RFA and MWA, LA was less effective in reducing the volume of CMLNs of PTC.

Indexed as

Catheter AblationRadiofrequency AblationThyroid NeoplasmsHumansLymph NodesThyroid Cancer, Papillarymeta-analysismetastatic lymph nodespapillary thyroid carcinomasystematic reviewthermal ablation

Identifiers

PMID36072932
PMCPMC9441577
OpenAlexW4292566196

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.