Evidence map›Paper›PMID 36072671›Full record

ArticleFrontiers in genetics2022

Efficacy of Long-Term Treatment of Autosomal Recessive Hypercholesterolemia With Lomitapide: A Subanalysis of the Pan-European Lomitapide Study.

Laura D'Erasmo, Antonina Giammanco, Patrizia Suppressa, Chiara Pavanello, Gabriella Iannuzzo, Alessia Di Costanzo, Daniele Tramontano, Ilenia Minicocci, Simone Bini, Anja Vogt and 5 more

Open access · goldAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Frontiers in genetics, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed, 1 pooled it
2.6field-weighted citation impact, top 10% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed, 1 synthesis or guideline pooled it, 12 citations in OpenAlex.

  1. Pooled it
  2. Review
  3. Article
  4. Advances in Treatment of Dyslipidemia.International journal of molecular sciences · 2023
    Review
  5. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

15 authors at 8 institutions in 3 countries.

Laura D'ErasmoDepartment of Translational and Precision Medicine, Sapienza University of Rome, Rome, Italy.
Antonina GiammancoDipartimento di Promozione Della Salute Materno Infantile, Medicina Interna e Specialistica Di Eccellenza "G. D'Alessandro" (PROMISE), Università Degli Studidi Palermo, Palermo, Italy.
Patrizia SuppressaDepartment of Internal Medicine and Rare Diseases Centre "C. Frugoni", University Hospital of Bari, Bari, Italy.
Chiara PavanelloCentro E. Grossi Paoletti, Dipartimento di Scienze Farmacologiche e Biomolecolari, Università Degli Studi di Milano, Milan, Italy.
Gabriella IannuzzoDepartment of Clinical Medicine and Surgery, Federico II University, Naples, Italy.
Alessia Di CostanzoDepartment of Translational and Precision Medicine, Sapienza University of Rome, Rome, Italy.
Daniele TramontanoDepartment of Translational and Precision Medicine, Sapienza University of Rome, Rome, Italy.
Ilenia MinicocciDepartment of Translational and Precision Medicine, Sapienza University of Rome, Rome, Italy.
Simone BiniDepartment of Translational and Precision Medicine, Sapienza University of Rome, Rome, Italy.
Anja VogtMedizinische Klinik und Poliklinik IV, Klinikum der Universität München, Munich, Germany.
Kim StewardsDepartment of Internal Medicine, University Medical Centre Rotterdam, Rotterdam, Netherlands.
Jeanine Roeters Van LennepDepartment of Internal Medicine, University Medical Centre Rotterdam, Rotterdam, Netherlands.
Stefano BertoliniDepartment of Internal Medicine, University of Genova, Genova, Italy.
Marcello ArcaDepartment of Translational and Precision Medicine, Sapienza University of Rome, Rome, Italy.
Italian and European Working Group on Lomitapide in HoFH
Sapienza University of Rome · ITRotterdam University of Applied Sciences · NLFederico II University Hospital · ITLMU Klinikum · DEUniversity of Bari Aldo Moro · ITUniversity of Genoa · ITUniversity of Milan · ITUniversity of Palermo · IT

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

PubMed holds no abstract for this paper.

Indexed as

autosomal recessive hypercholesterolaemiaefficacyLDL-Clomitapidelong-termrare diseaseReal-world studysafety

Identifiers

PMID36072671
PMCPMC9442671
OpenAlexW4293169112

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.