Evidence map›Paper›PMID 36072604›Full record

ArticleFrontiers in immunology2022

Innate immune responses to three doses of the BNT162b2 mRNA SARS-CoV-2 vaccine.

Marina Saresella, Federica Piancone, Ivana Marventano, Ambra Hernis, Daria Trabattoni, Mattia Invernizzi, Francesca La Rosa, Mario Clerici

Open access · goldAbstract read
In one paragraph

Article in Frontiers in immunology, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 18 papers.

0numbers the graph read from it
0cells of the map it votes in
18citing papers in PubMed
2.1field-weighted citation impact, top 11% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

18 citing papers in PubMed, 22 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 2 institutions in 1 country.

Marina SaresellaIRCCS Fondazione Don Carlo Gnocchi, Milan, Italy.
Federica PianconeIRCCS Fondazione Don Carlo Gnocchi, Milan, Italy.
Ivana MarventanoIRCCS Fondazione Don Carlo Gnocchi, Milan, Italy.
Ambra HernisIRCCS Fondazione Don Carlo Gnocchi, Milan, Italy.
Daria TrabattoniDepartments of Biomedical and Clinical Sciences L. Sacco, University of Milan, Milan, Italy.
Mattia InvernizziEnvironmental Science and Policy, University of Milan, Milan, Italy.
Francesca La RosaIRCCS Fondazione Don Carlo Gnocchi, Milan, Italy.
Mario ClericiIRCCS Fondazione Don Carlo Gnocchi, Milan, Italy.
Don Carlo Gnocchi Foundation · ITUniversity of Milan · IT

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

To explore the effects of SARS-CoV-2-mRNA vaccines on innate immune responses we enrolled 58 individuals who received 3 doses of the BNT162b2 vaccine in a longitudinal study; 45 of these individuals had never been SARS-CoV-2 infected. Results showed that vaccination significantly increased: 1) classical and intermediate inflammatory monocytes, 2) CD56

Indexed as

COVID-19COVID-19 VaccinesBNT162 VaccineHumansImmunity, InnateLongitudinal StudiesmRNA VaccinesRNA, MessengerSARS-CoV-2Vaccines, SyntheticBNT162 VaccineCOVID-19 VaccinesmRNA VaccinesRNA, MessengerVaccines, SyntheticIFN-γinnate immunityKIRmRNA vaccinenatural killer

Identifiers

PMID36072604
PMCPMC9443429
OpenAlexW4292608745

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.