Evidence map›Paper›PMID 36072579›Full record

ArticleFrontiers in immunology2022

Role of Pannexin-1-P2X7R signaling on cell death and pro-inflammatory mediator expression induced by

Andrea V Loureiro, Lauro I Moura-Neto, Conceição S Martins, Pedro I M Silva, Matheus B S Lopes, Renata F C Leitão, Juliana M Coelho-Aguiar, Vivaldo Moura-Neto, Cirle A Warren, Deiziane V S Costa and 1 more

Open access · goldAbstract read
In one paragraph

Article in Frontiers in immunology, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 18 papers.

0numbers the graph read from it
0cells of the map it votes in
18citing papers in PubMed
2.3field-weighted citation impact, top 10% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

18 citing papers in PubMed, 23 citations in OpenAlex.

  1. Article
  2. CSPG4 Mediates Inflammatory, Cell Death, and Senescence Responses in Enteric Glia Exposed to Clostridioides difficile Toxins.FASEB journal : official publication of the Federation of American Societies for Experimental Biology · 2026
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  6. The Regulatory Mechanisms of Treponema pallidum Enolase on Macrophages: From Enzymatic Activity to Signal Transduction.FASEB journal : official publication of the Federation of American Societies for Experimental Biology · 2025
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors at 3 institutions in 2 countries.

Andrea V LoureiroDepartment of Morphology, School of Medicine, Federal University of Ceará, Fortaleza, Ceará, Brazil.
Lauro I Moura-NetoDepartment of Morphology, School of Medicine, Federal University of Ceará, Fortaleza, Ceará, Brazil.
Conceição S MartinsDepartment of Morphology, School of Medicine, Federal University of Ceará, Fortaleza, Ceará, Brazil.
Pedro I M SilvaDepartment of Morphology, School of Medicine, Federal University of Ceará, Fortaleza, Ceará, Brazil.
Matheus B S LopesDepartment of Morphology, School of Medicine, Federal University of Ceará, Fortaleza, Ceará, Brazil.
Renata F C LeitãoDepartment of Morphology, School of Medicine, Federal University of Ceará, Fortaleza, Ceará, Brazil.
Juliana M Coelho-AguiarPaulo Niemeyer Brain Institute, Federal University of Rio de Janeiro, UFRJ, Rio de Janeiro, Rio de Janeiro, Brazil.
Vivaldo Moura-NetoPaulo Niemeyer Brain Institute, Federal University of Rio de Janeiro, UFRJ, Rio de Janeiro, Rio de Janeiro, Brazil.
Cirle A WarrenDivision of Infectious Diseases and International Health, University of Virginia, Charlottesville, VA, United States.
Deiziane V S CostaDivision of Infectious Diseases and International Health, University of Virginia, Charlottesville, VA, United States.
Gerly A C BritoDepartment of Morphology, School of Medicine, Federal University of Ceará, Fortaleza, Ceará, Brazil.
Universidade Federal do Ceará · BRUniversidade Federal do Rio de Janeiro · BRUniversity of Virginia · US

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

PubMed holds no abstract for this paper.

Indexed as

Bacterial ToxinsClostridioides difficileConnexinsNerve Tissue ProteinsReceptors, Purinergic P2X7AnimalsAnnexinsCaspase 3Cell DeathInflammation MediatorsMaleMiceMice, Inbred C57BLNeurogliaPhosphatidylserinesAnnexinsBacterial ToxinsCaspase 3ConnexinsInflammation MediatorsNerve Tissue ProteinsP2rx7 protein, mousePanx1 protein, mousePhosphatidylserinesReceptors, Purinergic P2X7Clostridioides difficileClostridioides difficile infectionEnteric gliaP2X7RPannexin-1

Identifiers

PMID36072579
PMCPMC9442043
OpenAlexW4292582767

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.