Evidence map›Paper›PMID 36071984›Full record

ReviewExploration of targeted anti-tumor therapy2022

Roles of calcium signaling in cancer metastasis to bone.

Tianying Xie, Sitong Chen, Jiang Hao, Pengfei Wu, Xuelian Gu, Haifeng Wei, Zhenxi Li, Jianru Xiao

Open access · diamondAbstract readReview
In one paragraph

Review in Exploration of targeted anti-tumor therapy, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers.

0numbers the graph read from it
0cells of the map it votes in
9citing papers in PubMed
1.1field-weighted citation impact, top 23% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

9 citing papers in PubMed, 14 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 3 institutions in 1 country.

Tianying XieSchool of Health Science and Engineering, University of Shanghai for Science and Technology, Shanghai 200093, China.ORCID https://orcid.org/0000-0001-7581-9115
Sitong ChenSchool of Health Science and Engineering, University of Shanghai for Science and Technology, Shanghai 200093, China.
Jiang HaoDepartment of Orthopedic Oncology, Shanghai Changzheng Hospital, Shanghai 200003, China.
Pengfei WuCenter for Medical Genetics, School of Life Sciences, Central South University, Changsha 410008, Hunan, China.
Xuelian GuSchool of Health Science and Engineering, University of Shanghai for Science and Technology, Shanghai 200093, China.
Haifeng WeiDepartment of Orthopedic Oncology, Shanghai Changzheng Hospital, Shanghai 200003, China.
Zhenxi LiSchool of Health Science and Engineering, University of Shanghai for Science and Technology, Shanghai 200093, China.ORCID https://orcid.org/0000-0002-7220-6177
Jianru XiaoSchool of Health Science and Engineering, University of Shanghai for Science and Technology, Shanghai 200093, China.
University of Shanghai for Science and Technology · CNShanghai Changzheng Hospital · CNCentral South University · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Bone metastasis is a frequent complication for cancers and an important reason for the mortality in cancer patients. After surviving in bone, cancer cells can cause severe pain, life-threatening hypercalcemia, pathologic fractures, spinal cord compression, and even death. However, the underlying mechanisms of bone metastasis were not clear. The role of calcium (Ca

Indexed as

Bone metastasiscalciumcalcium channelscalcium-sensing receptorcalmodulin

Identifiers

PMID36071984
PMCPMC9446157
OpenAlexW4293727591

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.