Evidence map›Paper›PMID 36071868›Full record

ArticleOxidative medicine and cellular longevity2022

Tripeptide Leu-Pro-Phe from Corn Protein Hydrolysates Attenuates Hyperglycemia-Induced Neural Tube Defect in Chicken Embryos.

Chang-Yu Yan, Jie Sun, Gui-Yuan Yu, Jiang-Han-Zi Liu, Rong-Ping Huang, Shao-Cong Han, Qiong-Yi Zhang, Xiao-Min Li, Jian-Gang Yan, Hiroshi Kurihara and 3 more

Open access · hybridAbstract read
In one paragraph

Article in Oxidative medicine and cellular longevity, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
1.0field-weighted citation impact, top 27% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed, 9 citations in OpenAlex.

  1. Article
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

13 authors at 2 institutions in 1 country.

Chang-Yu YanGuangdong Engineering Research Center of Chinese Medicine & Disease Susceptibility, College of Pharmacy, Jinan University, Guangzhou 510632, China.
Jie SunGuangdong Engineering Research Center of Chinese Medicine & Disease Susceptibility, College of Pharmacy, Jinan University, Guangzhou 510632, China.
Gui-Yuan YuPerfect (Guangdong) Co., Ltd., Zhongshan 528451, China.
Jiang-Han-Zi LiuGuangdong Engineering Research Center of Chinese Medicine & Disease Susceptibility, College of Pharmacy, Jinan University, Guangzhou 510632, China.
Rong-Ping HuangYunnan University of Traditional Chinese Medicine, Kunming 650500, China.
Shao-Cong HanYunnan University of Traditional Chinese Medicine, Kunming 650500, China.
Qiong-Yi ZhangGuangdong Engineering Research Center of Chinese Medicine & Disease Susceptibility, College of Pharmacy, Jinan University, Guangzhou 510632, China.
Xiao-Min LiPerfect (Guangdong) Co., Ltd., Zhongshan 528451, China.
Jian-Gang YanPerfect (Guangdong) Co., Ltd., Zhongshan 528451, China.
Hiroshi KuriharaGuangdong Engineering Research Center of Chinese Medicine & Disease Susceptibility, College of Pharmacy, Jinan University, Guangzhou 510632, China.
Wei-Xi LiYunnan University of Traditional Chinese Medicine, Kunming 650500, China.ORCID https://orcid.org/0000-0002-6614-9508
Yi-Fang LiGuangdong Engineering Research Center of Chinese Medicine & Disease Susceptibility, College of Pharmacy, Jinan University, Guangzhou 510632, China.ORCID https://orcid.org/0000-0002-3356-3702
Rong-Rong HeGuangdong Engineering Research Center of Chinese Medicine & Disease Susceptibility, College of Pharmacy, Jinan University, Guangzhou 510632, China.ORCID https://orcid.org/0000-0001-5505-5672
Jinan University · CNYunnan University of Traditional Chinese Medicine · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Neural tube defect (NTD) is the most common and severe embryopathy causing embryonic malformation and even death associated with gestational diabetes mellitus (GDM). Leu-Pro-Phe (LPF) is an antioxidative tripeptide isolated from hydrolysates of corn protein. However, the biological activity of LPF

Indexed as

HyperglycemiaNeural Tube DefectsProtein HydrolysatesAnimalsAntioxidantsChick EmbryoChickensDipeptidesGlucoseZea maysAntioxidantsDipeptidesGlucoseleucylprolineProtein Hydrolysates

Identifiers

PMID36071868
PMCPMC9444464
OpenAlexW4293526005

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.