ArticleFrontiers in pharmacology2022
Structural modification of octadecanoic acid-3,4-tetrahydrofuran diester and the acaricidal activity and mechanism of its derivatives against
Article in Frontiers in pharmacology, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.
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Who cites it
3 citing papers in PubMed, 5 citations in OpenAlex.
- In Vivo Acaricidal Effect of Linoleic Acid and Olive Oil Against Psoroptes cuniculi Mites in Experimentally Infested Rabbits.Acta parasitologica · 2026Article
- Natural Products as Mite Control Agents in Animals: A Review.Molecules (Basel, Switzerland) · 2023Review
- Essential Oils againstMolecules (Basel, Switzerland) · 2022Review
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Authors and funding
16 authors at 1 institution in 1 country.
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Abstract
Octadecanoic acid-3,4-tetrahydrofuran diester is a compound with acaricidal activity isolated and extracted from neem oil. In this study, a series of derivatives were obtained by structural modification of octadecanoic acid-3,4-tetrahydrofuran diester. The acaricidal activity of these derivatives indicated that introduction of benzyloxy substitution at the 2-position of the furan ring and the formation of a benzoate at the 3,4-position of the furan ring (benzoic acid-2-benzyloxy-3,4-tetrahydrofuran diester) could enhance the acaricidal activity. At concentration of 20, 10, and 5 mg/ml, the median lethal time (LT
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