Evidence map›Paper›PMID 36071679›Full record

ArticlePaediatric and perinatal epidemiology2023

Organic food consumption and fecundability in a preconception cohort study of Danish couples trying to conceive.

Sissel Jessen Weissert, Ellen Margrethe Mikkelsen, Bjarke H Jacobsen, Elizabeth E Hatch, Amelia K Wesselink, Lauren A Wise, Kenneth J Rothman, Henrik T Sørensen, Anne Sofie Dam Laursen

Open access · hybridAbstract read
In one paragraph

Article in Paediatric and perinatal epidemiology, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
0.6field-weighted citation impact, top 31% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed, 3 citations in OpenAlex.

  1. Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 3 institutions in 2 countries.

Sissel Jessen WeissertDepartment of Clinical Epidemiology, Aarhus University and Aarhus University Hospital, Aarhus, Denmark.ORCID 0000-0002-4775-3320
Ellen Margrethe MikkelsenDepartment of Clinical Epidemiology, Aarhus University and Aarhus University Hospital, Aarhus, Denmark.
Bjarke H JacobsenDepartment of Clinical Epidemiology, Aarhus University and Aarhus University Hospital, Aarhus, Denmark.
Elizabeth E HatchDepartment of Epidemiology, Boston University School of Public Health, Boston, Massachusetts, USA.
Amelia K WesselinkDepartment of Epidemiology, Boston University School of Public Health, Boston, Massachusetts, USA.ORCID 0000-0002-3929-4451
Lauren A WiseDepartment of Epidemiology, Boston University School of Public Health, Boston, Massachusetts, USA.ORCID 0000-0003-2138-3752
Kenneth J RothmanRTI Health solutions, Research Triangle Park, North Carolina, USA.
Henrik T SørensenDepartment of Clinical Epidemiology, Aarhus University and Aarhus University Hospital, Aarhus, Denmark.
Anne Sofie Dam LaursenDepartment of Clinical Epidemiology, Aarhus University and Aarhus University Hospital, Aarhus, Denmark.ORCID 0000-0003-2827-0582
Aarhus University Hospital · DKBoston University · USRTI Health Solutions · US

Funding

An internet-based preconception cohort study in North America and DenmarkR01HD086742 · NICHD · BOSTON UNIVERSITY MEDICAL CAMPUS · PI LAUREN A WISE · 2016 to 2026
$6.7M
NICHD NIH HHS R01 HD086742
6 · The paper itself

Abstract

backgroundLittle is known about potential health effects of eating organic food in relation to reproduction.

objectiveWe examined associations between organic food consumption and fecundability.

methodsData were derived from a preconception cohort study of Danish couples trying to conceive (SnartForaeldre.dk, SF). Participants completed a baseline questionnaire on socio-demographics, anthropometrics and lifestyle and a validated food-frequency questionnaire, which included questions on proportions of organic food consumed within six food groups. Participants were followed up with bimonthly questionnaires for up to 12 months or until pregnancy. Analyses were restricted to 2061 participants attempting pregnancy for ≤6 cycles at enrollment and 1303 with <3 cycles. Fecundability ratios (FRs) and 95% confidence intervals (CI) were estimated by proportional probabilities regression models adjusted for potential confounders including age, lifestyle and socioeconomic factors. Associations were examined for vegetables, fruits, cereals, dairy products, eggs and meat, separately, and for the overall pattern of organic food consumption (organic sum score).

resultsThe final analytic sample comprised 2069 participants. In the full cohort, organic food consumption was not meaningfully associated with fecundability. Among participants <3 cycles of pregnancy attempt at study entry (n = 1303), the FR was 1.11 (95% CI 0.93, 1.33) for the category 'less than half', for 'more than half' the FR was 1.17 (95% CI 0.99, 1.38) and for 'almost everything' the FR was 1.12 (95% CI 0.97, 1.28).

conclusionHigher consumption of organic foods was not meaningfully associated with fecundability, although slightly greater fecundability was seen among participants with <3 cycles of pregnancy attempt time.

Indexed as

FertilityFood, OrganicCohort StudiesDenmarkFemaleHumansPregnancyProspective Studiesdietfecundabilityfertilityorganic foodpreconception cohort

Identifiers

PMID36071679
PMCPMC10087289
OpenAlexW4294991978

What OpenQuestion holds

Textmetadata
LicenceCC BY
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.