Evidence map›Paper›PMID 36071616›Full record

ArticleJournal of cerebral blood flow and metabolism : official journal of the International Society of Cerebral Blood Flow and Metabolism2023

Increased rates of brain protein synthesis during [N1,N2] sleep: L-[1-

Dante Picchioni, Kathleen C Schmidt, Inna Loutaev, Adriana J Pavletic, Carrie Sheeler, Shrinivas Bishu, Thomas J Balkin, Carolyn B Smith

Open access · bronzeAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Journal of cerebral blood flow and metabolism : official journal of the International Society of Cerebral Blood Flow and Metabolism, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
0.2field-weighted citation impact, top 50% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed, 2 citations in OpenAlex.

  1. Review
  2. Article
  3. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 3 institutions in 1 country.

Dante PicchioniSection on Neuroadaptation and Protein Metabolism, National Institute of Mental Health, Bethesda, MD, USA.
Kathleen C SchmidtSection on Neuroadaptation and Protein Metabolism, National Institute of Mental Health, Bethesda, MD, USA.
Inna LoutaevSection on Neuroadaptation and Protein Metabolism, National Institute of Mental Health, Bethesda, MD, USA.
Adriana J PavleticOffice of the Clinical Director, National Institute of Mental Health, Bethesda, MD, USA.
Carrie SheelerSection on Neuroadaptation and Protein Metabolism, National Institute of Mental Health, Bethesda, MD, USA.
Shrinivas BishuSection on Neuroadaptation and Protein Metabolism, National Institute of Mental Health, Bethesda, MD, USA.
Thomas J BalkinBehavioral Biology Branch, Walter Reed Army Institute of Research, Silver Spring, MD, USA.ORCID 0000-0002-4177-7719
Carolyn B SmithSection on Neuroadaptation and Protein Metabolism, National Institute of Mental Health, Bethesda, MD, USA.
National Institute of Mental Health · USNational Institute of Neurological Disorders and Stroke · USWalter Reed Army Institute of Research · US

Funding

Magnetic Resonance Imaging of Human Brain Anatomy and FunctionZIANS003027 · NINDS · NATIONAL INSTITUTE OF NEUROLOGICAL DISORDERS AND STROKE · PI DUYN, JEFF · 2009 to 2025
$31.2M
Psychiatry Consultation Liaison Service ResearchZIAMH002922 · NIMH · NATIONAL INSTITUTE OF MENTAL HEALTH · PI PAO, MARYLAND · 2009 to 2025
$11.5M
Cerebral Protein Synthesis During Sleep and Memory ConsolidationZIAMH002936 · NIMH · NATIONAL INSTITUTE OF MENTAL HEALTH · PI BEEBE SMITH, CAROLYN · 2012 to 2021
$2.4M
Intramural NIH HHS ZIA MH002936Intramural NIH HHS ZIA NS003027
6 · The paper itself

Abstract

During sleep, reduced brain energy demands provide an opportunity for biosynthetic processes like protein synthesis. Sleep is required for some forms of memory consolidation which requires

Indexed as

Research SubjectsSleepBrainHumansLeucinePositron-Emission TomographyLeucineLeucineN2positron emission tomographyprotein synthesissleep

Identifiers

PMID36071616
PMCPMC9875345
OpenAlexW4294942937

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.