ArticleJournal of diabetes2022
Association between triglyceride glucose index and carotid intima-media thickness in obese and nonobese adults.
Article in Journal of diabetes, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 14 papers.
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Who cites it
14 citing papers in PubMed.
- Carotid Atherosclerosis and Metabolic Characteristics Among High-Risk Cardiovascular Populations of Four Ethnic Groups - Yunnan Province, China, 2024.China CDC weekly · 2026Article
- The impact of triglyceride-glucose index on short-term prognosis in patients with acute myocarditis.BMC cardiovascular disorders · 2026Article
- Sex-specific performance of composite metabolic-adiposity indices in identifying hypertension and carotid atherosclerosis: a cross-sectional study of 154,873 Chinese adults.Scientific reports · 2026Article
- Association of triglyceride-glucose index with carotid atherosclerosis in the general population: a case-control study of 14,535 participants.BMC cardiovascular disorders · 2026Article
- Association between the triglyceride-glucose index and subclinical atherosclerosis in asymptomatic adults: a large cross-sectional study of a health check-up population.Frontiers in cardiovascular medicine · 2026Article
- Association Between Carotid Intima-Media Thickness and Novel Lipid Parameters in Hypertensive Patients.High blood pressure & cardiovascular prevention : the official journal of the Italian Society of Hypertension · 2025Article
- Association between triglyceride-glucose index and carotid atherosclerosis in Chinese steelworkers: a cross-sectional study.Scientific reports · 2025Article
- Relationship Between the TyGH Index (Based on Triglycerides and HbA1c) and Diabetic Kidney Disease in Patients with Type 2 Diabetes: A Real-World Study.Diabetes, metabolic syndrome and obesity : targets and therapy · 2025Article
- The Impact of Triglyceride-Glucose Index on Carotid Atherosclerosis: A Prospective Cohort Study in Middle Aged and Elderly Low-Income in Rural Chinese.Risk management and healthcare policy · 2025Article
- Application of TyG index and carotid ultrasound parameters in the prediction of ischemic stroke.Frontiers in endocrinology · 2025Article
- Relationship between triglyceride-glucose index and endometriosis: a cross-sectional analysis.BMC women's health · 2024Article
- Associations between insulin resistance indices and subclinical atherosclerosis: A contemporary review.American journal of preventive cardiology · 2024Review
- Triglyceride-glucose index is associated with poor prognosis in acute coronary syndrome patients with prior coronary artery bypass grafting undergoing percutaneous coronary intervention.Cardiovascular diabetology · 2023Article
- Association between triglyceride glucose index and carotid intima-media thickness in obese and nonobese adults.Journal of diabetes · 2022Article
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20 authors.
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Abstract
backgroundThe triglyceride glucose (TyG) index is closely associated with subclinical atherosclerosis. However, the association remains inconclusive among obese and nonobese individuals.
methodsThis prospective study was conducted in 5751 adults with normal carotid intima-media thickness (CIMT) at baseline. We divided the population into four groups based on the TyG index, which was calculated by the following formula: Ln (fasting triglycerides [mg/dL] × fasting glucose [mg/dL]/2). Information on CIMT was acquired by ultrasonography. Incident elevated CIMT was defined as IMT values greater than 0.9 mm at follow-up. Odds ratios (ORs) and 95% confidence intervals (CIs) of the associations between TyG index and elevated CIMT were estimated using multivariable logistic regression models.
resultsAfter a median follow-up of 4.3 years, 722 (12.6%) individuals had progressed to elevated CIMT. Compared with the second quartile of the TyG index, the first and fourth quartile both conferred higher risks of elevated CIMT after adjusting for potential confounders. In the total population, the ORs for the first and fourth quartile were 1.29 (95% CI, 1.00-1.66) and 1.42 (95% CI, 1.11-1.83), respectively. Restricted cubic splines demonstrated an approximately U-shaped association between TyG index and elevated CIMT among the total and nonobese adults (P for nonlinearity <.05), but not in those with general or abdominal obesity.
conclusionsA U-shaped association was observed between TyG index and elevated CIMT only among nonobese Chinese adults.
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