Evidence map›Paper›PMID 36071535›Full record

ArticleSystematic reviews2022

Efficacy and safety of wound infiltration modalities for postoperative pain management after cesarean section: a systematic review and network meta-analysis protocol.

Semagn Mekonnen Abate, Getachew Mergia, Solomon Nega, Bivash Basu, Moges Tadesse

Open access · goldAbstract read
In one paragraph

Article in Systematic reviews, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
1.7field-weighted citation impact, top 16% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed, 8 citations in OpenAlex.

  1. Trial
  2. Trial
  3. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 1 institution in 1 country.

Semagn Mekonnen AbateDepartment of Anesthesiology, College of Health Sciences and Medicine, Dilla University, Dilla, Ethiopia. semmek17@gmail.com.ORCID 0000-0001-5661-8537
Getachew MergiaDepartemnt of Obstetrics and Gynecology, College of Health Sciences and Medicine, Dilla University, Dilla, Ethiopia.
Solomon NegaDepartemnt of Internal Medicine, College of Health Sciences and Medicine, Dilla University, Dilla, Ethiopia.
Bivash BasuDepartment of Anesthesiology, College of Health Sciences and Medicine, Dilla University, Dilla, Ethiopia.
Moges TadesseSchool of Public Health, College of Health Sciences and Medicine, Dilla University, Dilla, Ethiopia.
Dilla University · ET

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundPostoperative pain after a cesarean section has negative consequences for the mother during the postoperative period. Over the years, various postoperative pain management strategies have been used following cesarean section. Opioid-based analgesics and landmark approaches have negative side effects, while ultrasound-based regional analgesia necessitates resources and experience, but various wound infiltration adjuvants are innovative with few side effects and are simple to use. The efficacy and safety of each adjuvant, however, are unknown and require further investigation.

objectiveThis network meta-analysis is intended to provide the most effective wound infiltration drugs for postoperative management after cesarean section.

methodA comprehensive search will be conducted in PubMed/MEDLINE, Cochrane Library, Science Direct, CINHAL, and LILACS without date and language restrictions. All randomized trials comparing the effectiveness of wound infiltration drugs for postoperative pain management after cesarean section will be included. Data extraction will be conducted independently by two authors. The quality of studies will be evaluated using the Cochrane risk of bias tool, and the overall quality of the evidence will be determined by GRADEpro software. DISCUSSION: The rate of postoperative acute and chronic pain is very high which has a huge impact on the mother, family, healthcare practitioners, and healthcare delivery. It is a basic human right to give every patient with postoperative pain treatment that is realistic in terms of resources, technique, cost, and adverse event profile. SYSTEMATIC REVIEW REGISTRATION: PROSPERO CRD42021268774.

Indexed as

AnalgesiaCesarean SectionAnalgesics, OpioidFemaleHumansNetwork Meta-Analysis as TopicPain ManagementPostoperative PainPregnancySystematic Reviews as TopicAnalgesics, OpioidCesarean sectionPostoperative painWound infiltration

Identifiers

PMID36071535
PMCPMC9450460
OpenAlexW4294876504

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.