Evidence map›Paper›PMID 36071311›Full record

ArticleOphthalmology and therapy2022

Cost-Effectiveness of Presbyopia Correction Among Seven Strategies of Bilateral Cataract Surgery Based on a Prospective Single-Blind Two-Center Trial in China.

Qianqian Lan, Yiyun Liu, Fan Xu, Min Li, Yaxin Li, Tingting Yang, Tong Sun, Gang Yao, Baikai Ma, Liyuan Tao and 4 more

Registry-linked trialAbstract read
In one paragraph

Article in Ophthalmology and therapy, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT04265846 (Prospective Clinical Study of Different Intraocular Lens Implantation Designed for the Correction of Presbyopia), which is not on this map. Cited by 6 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT04265846 unknown statusnot on this map

Prospective Clinical Study of Different Intraocular Lens Implantation Designed for the Correction of Presbyopia

TypeobservationalSponsorPeking University Third HospitalRan2020 to 2022Enrolled140ConditionsPresbyopia, Cataract SenileArmsbifocal IOL, mix bifocal IOL, trifocal IOL, EDOF IOL, different IOLs
3 · Its place in the literature

Who cites it

6 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Surgical interventions for presbyopia.The Cochrane database of systematic reviews · 2025
    Pooled it
  2. Article
  3. Article
  4. Article
  5. Article
  6. Peripheral Defocus and Myopia Management: A Mini-Review.Korean journal of ophthalmology : KJO · 2023
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

14 authors.

Qianqian LanDepartment of Ophthalmology, Peking University Third Hospital and Beijing Key Laboratory of Restoration of Damaged Ocular Nerve, Peking University Third Hospital, 49 North Garden Road, Haidian District, Beijing, 100191, China.ORCID http://orcid.org/0000-0001-8917-6659
Yiyun LiuDepartment of Ophthalmology, Peking University Third Hospital and Beijing Key Laboratory of Restoration of Damaged Ocular Nerve, Peking University Third Hospital, 49 North Garden Road, Haidian District, Beijing, 100191, China.
Fan XuInstitute of Ophthalmic Diseases, Guangxi Academy of Medical Sciences, Guangxi Health Commission Key Laboratory of Ophthalmology and Related Systemic Diseases Artificial Intelligence Screening Technology, Department of Ophthalmology, the People's Hospital of Guangxi Zhuang Autonomous Region, No.6, Taoyuan Road, Nanning, 530021, Guangxi Zhuang Autonomous Region, China.
Min LiInstitute of Ophthalmic Diseases, Guangxi Academy of Medical Sciences, Guangxi Health Commission Key Laboratory of Ophthalmology and Related Systemic Diseases Artificial Intelligence Screening Technology, Department of Ophthalmology, the People's Hospital of Guangxi Zhuang Autonomous Region, No.6, Taoyuan Road, Nanning, 530021, Guangxi Zhuang Autonomous Region, China.
Yaxin LiDepartment of Ophthalmology, Peking University Third Hospital and Beijing Key Laboratory of Restoration of Damaged Ocular Nerve, Peking University Third Hospital, 49 North Garden Road, Haidian District, Beijing, 100191, China.
Tingting YangDepartment of Ophthalmology, Peking University Third Hospital and Beijing Key Laboratory of Restoration of Damaged Ocular Nerve, Peking University Third Hospital, 49 North Garden Road, Haidian District, Beijing, 100191, China.
Tong SunDepartment of Ophthalmology, Peking University Third Hospital and Beijing Key Laboratory of Restoration of Damaged Ocular Nerve, Peking University Third Hospital, 49 North Garden Road, Haidian District, Beijing, 100191, China.
Gang YaoInstitute of Ophthalmic Diseases, Guangxi Academy of Medical Sciences, Guangxi Health Commission Key Laboratory of Ophthalmology and Related Systemic Diseases Artificial Intelligence Screening Technology, Department of Ophthalmology, the People's Hospital of Guangxi Zhuang Autonomous Region, No.6, Taoyuan Road, Nanning, 530021, Guangxi Zhuang Autonomous Region, China.
Baikai MaDepartment of Ophthalmology, Peking University Third Hospital and Beijing Key Laboratory of Restoration of Damaged Ocular Nerve, Peking University Third Hospital, 49 North Garden Road, Haidian District, Beijing, 100191, China.
Liyuan TaoResearch Center of Clinical Epidemiology, Peking University Third Hospital, 49 North Garden Road, Haidian District, Beijing, 100191, China.
Xin XiaoInstitute of Ophthalmic Diseases, Guangxi Academy of Medical Sciences, Guangxi Health Commission Key Laboratory of Ophthalmology and Related Systemic Diseases Artificial Intelligence Screening Technology, Department of Ophthalmology, the People's Hospital of Guangxi Zhuang Autonomous Region, No.6, Taoyuan Road, Nanning, 530021, Guangxi Zhuang Autonomous Region, China.
Xing Lin FengSchool of Public Health, Peking University, 38 Xueyuan Road, Haidian District, Beijing, 100191, China. fxl@bjmu.edu.cn.ORCID http://orcid.org/0000-0003-3588-1859
Siming ZengInstitute of Ophthalmic Diseases, Guangxi Academy of Medical Sciences, Guangxi Health Commission Key Laboratory of Ophthalmology and Related Systemic Diseases Artificial Intelligence Screening Technology, Department of Ophthalmology, the People's Hospital of Guangxi Zhuang Autonomous Region, No.6, Taoyuan Road, Nanning, 530021, Guangxi Zhuang Autonomous Region, China. gxeye@126.com.
Hong QiDepartment of Ophthalmology, Peking University Third Hospital and Beijing Key Laboratory of Restoration of Damaged Ocular Nerve, Peking University Third Hospital, 49 North Garden Road, Haidian District, Beijing, 100191, China. doctorqihong@163.com.ORCID http://orcid.org/0000-0003-3066-8020

Funding

Guangxi clinical ophthalmic research center AD19245193Guangxi Medical Health Appropriate Technology Development and Application Project S2020077National Natural Science Foundation of China 81974128National Natural Science Foundation of China 82171022Natural Science Foundation of Guangxi Province 2021GXNSFBA075051Science and Technology Plan Project of Qingxiu District in Nanning City 2020036the Capital Health Research and Development of Special 2020-2-4097
6 · The paper itself

Abstract

introductionThe aim of this study was to explore a method to rank the cost-effectiveness of presbyopia correction in diverse strategies of bilateral cataract surgery to provide references for healthcare policymakers in rationalizing resource utilization and surgeons in customizing patient management.

methodsThe cost-effectiveness analysis based on a prospective single-blind two-center clinical trial included seven strategies in bilateral cataract surgery: monofocal, monovision, diffractive bifocal, blended, refractive bifocal, trifocal, and extended depth of focus (EDOF) strategies. The effectiveness according to the objective spectacle independence rate (hereafter "rate", a novel indicator defined as the proportion of patients with binocular uncorrected distance, intermediate and near visual acuity all better than 0.1 logMAR, logarithm of the minimum angle of resolution), costs, average cost-effectiveness ratios (ACERs, $/1% rate), and incremental cost-effectiveness ratios (ICERs, $/1% incremental rate) were estimated.

resultsIn 194 participants (388 eyes), the trifocal strategy achieved the highest rate [93.10% (95% confidence interval (CI) 83.8-102.35%)]. The refractive bifocal strategy had the minimum ACER [$45.54/1% rate (95% CI 34.57-56.50)], followed by the blended [$59.10/1% rate (95% CI 31.72-86.48)], diffractive bifocal [$69.06/1% rate (95% CI 30.89-107.21)], EDOF [$72.85/1% rate (95% CI 52.02-93.70)], trifocal [$93.01/1% rate (95% CI 83.23-102.79)], monovision [$136.83/1% rate (95% CI - 55.40 to 329.14)], and monofocal [$264.45/1% rate (95% CI - 97.45 to 626.55)] strategies. Compared with the refractive bifocal strategy, the probabilities that the trifocal strategy (ICER $289.74/1% incremental rate) is very cost-effective and cost-effective were 81.7% and 93.2%, respectively, at the wiliness-to-pay threshold of one and three times China's annual disposable income per capita in 2021 per 10% incremental rates.

conclusionsCost-effectiveness analysis with ACER and ICER according to objective spectacle independence rate is a helpful tool to identify highly cost-effective presbyopia-correcting strategies in cataract surgery for clinical and policy decisions.

trial registrationClinicaltrials.gov (NCT04265846).

Indexed as

Average cost-effectiveness ratioCataract surgeryCost-effectiveness analysisIncremental cost-effectiveness ratiosObjective spectacle independencePresbyopia correction

Identifiers

PMID36071311
PMCPMC9587195

What OpenQuestion holds

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Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.