Evidence map›Paper›PMID 36071289›Full record

ArticleMedical oncology (Northwood, London, England)2022

The effect of ciprofloxacin on doxorubicin cytotoxic activity in the acquired resistance to doxorubicin in DU145 prostate carcinoma cells.

Asieh Davary Avareshk, Razieh Jalal, Jamileh Gholami

Abstract read
PubMed Publisher
In one paragraph

Article in Medical oncology (Northwood, London, England), 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
0.9field-weighted citation impact, top 25% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed, 6 citations in OpenAlex.

  1. Review
  2. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors at 1 institution in 1 country.

Asieh Davary Avareshk *Department of Chemistry, Faculty of Science, Ferdowsi University of Mashhad, Mashhad, Iran.
Razieh JalalDepartment of Chemistry, Faculty of Science, Ferdowsi University of Mashhad, Mashhad, Iran. razieh@um.ac.ir.ORCID http://orcid.org/0000-0001-7480-9812
Jamileh Gholami *Department of Chemistry, Faculty of Science, Ferdowsi University of Mashhad, Mashhad, Iran.
Ferdowsi University of Mashhad · IR

Funding

Ferdowsi University of Mashhad 3/44066
6 · The paper itself

Abstract

The present study aimed to assess the influence of ciprofloxacin (CIP) against the doxorubicin (DOX)-resistant androgen-independent prostate cancer DU145 cells. The DOX-resistant DU145 (DU145/DOX20) cells were established by exposing DU145 cells to the increasing concentrations of DOX. The antiproliferative effect of CIP was examined through employing MTT, colony formation, and 3D culture assays. DU145/DOX20 cells exhibited a twofold higher IC

Indexed as

Antineoplastic AgentsCarcinomaProstatic NeoplasmsCell Line, TumorCiprofloxacinDoxorubicinHumansMaleProstateAntineoplastic AgentsCiprofloxacinDoxorubicinCiprofloxacinClonogenicityDoxorubicin-resistant cellsMigration abilityProstate cancerSpheroid growth

Identifiers

PMID36071289
OpenAlexW4294897994

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.