ArticleJournal of experimental orthopaedics2022
An anatomically shaped medial meniscus prosthesis is able to partially restore the contact mechanics of the meniscectomized knee joint.
Article in Journal of experimental orthopaedics, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers.
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Who cites it
7 citing papers in PubMed, 16 citations in OpenAlex.
- Meniscal tissue engineering: Bridging clinical needs and experimental innovation.Journal of orthopaedic translation · 2026Review
- Novel prosthetic medial meniscus restores contact pressures to native values in a meniscectomized canine stifle.Veterinary surgery : VS · 2026Article
- Artificial medial and lateral meniscus prostheses mimic kinematics of the native meniscus without affecting knee joint motion: A cadaveric study.Journal of experimental orthopaedics · 2025Article
- High failure rate but promising clinical performance after implantation of a flexible medial meniscus prosthesis at 1-year follow-up.Knee surgery, sports traumatology, arthroscopy : official journal of the ESSKA · 2025Article
- A review of finite element modeling and surgical simulation of meniscal tear in knee joint: progress and challenges.Frontiers in medicine · 2025Review
- The Current State of Meniscus Replacements.Current reviews in musculoskeletal medicine · 2024Review
- The first-generation anatomical medial meniscus prosthesis led to unsatisfactory results: a first-in-human study.Knee surgery, sports traumatology, arthroscopy : official journal of the ESSKA · 2023Article
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Authors and funding
5 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
purposeThe aim of this study was to determine whether a flexible medial meniscus prosthesis is more capable of sharing loads with the direct tibiofemoral cartilage contact than the stiffer first-generation prosthesis. Additionally, the effect of the prosthesis on the tibial pressure distribution after total meniscectomy was investigated.
methodsIn an artificial knee joint, the relative amounts of load transferred through both meniscus prostheses and the direct tibiofemoral contact were assessed with pressure-sensitive sensors. Additionally, six cadaveric knee joints were loaded in a physiological environment. Tibial contact pressures were measured with an intact native meniscus, after total meniscectomy and after implantation of the second-generation meniscus prosthesis.
resultsWhereas the first generation of the meniscus prosthesis transferred virtually all the load from femur to tibia, the second-generation prosthesis allowed for load sharing with the direct tibiofemoral contact. No differences in load sharing were found between the native meniscus and the second-generation meniscus prosthesis. The prosthesis decreased peak and mean pressures on the medial tibial cartilage compared to meniscectomy. No significant differences in pressure were found between the native meniscus and the meniscus prosthesis.
conclusionsThe second-generation meniscus prosthesis presented in this study can share loads with the direct tibiofemoral contact, a characteristic that the first-generation prosthesis did not have. The flexible meniscus prosthesis significantly reduces the contact pressures on the medial tibial plateau after total meniscectomy. Although the biomechanical performance of the native meniscus could not be reproduced completely, the meniscus prosthesis may have the potential to relieve post-meniscectomy pain symptoms.
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Registered trials
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