Evidence map›Paper›PMID 36070939›Full record

ArticleInternal medicine (Tokyo, Japan)2023

The Postpartum Period Can Worsen Myelin Oligodendrocyte Glycoprotein Antibody-associated Encephalomyelitis.

Shizuka Yamamoto, Mitsutake Yano, Yuko Miyamoto, Takuya Hanaoka, Yoshihiro Nishida, Yasushi Kawano

Open access · diamondAbstract readCase Reports
PubMed Full text at PMC Publisher
In one paragraph

Article in Internal medicine (Tokyo, Japan), 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
0.3field-weighted citation impact, top 43% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed, 2 citations in OpenAlex.

  1. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 1 institution in 1 country.

Shizuka YamamotoDepartment of Obstetrics and Gynecology, Faculty of Medicine, Oita University, Japan.
Mitsutake YanoDepartment of Obstetrics and Gynecology, Faculty of Medicine, Oita University, Japan.
Yuko MiyamotoDepartment of Obstetrics and Gynecology, Faculty of Medicine, Oita University, Japan.
Takuya HanaokaDepartment of Neurology, Faculty of Medicine, Oita University, Japan.
Yoshihiro NishidaDepartment of Obstetrics and Gynecology, Faculty of Medicine, Oita University, Japan.
Yasushi KawanoDepartment of Obstetrics and Gynecology, Faculty of Medicine, Oita University, Japan.
Oita University · JP

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Myelin oligodendrocyte glycoprotein (MOG) antibodies are associated with relapsing inflammatory demyelinating disease. Pregnancy complicates the disease course, potentially leading to either symptom improvement or worsening. A 28-year-old woman with MOG antibody-associated encephalomyelitis had 2 pregnancies; her disease worsened during both postpartum periods despite continuing prednisolone and levetiracetam. The umbilical cord blood was positive for MOG antibodies following her second pregnancy, but neither baby had MOG antibody-associated disease. This is the first case report of MOG antibody-associated demyelinating disease that worsened postpartum despite continuous medication. Furthermore, we observed the placental transfer of MOG antibodies for the first time.

Indexed as

Demyelinating DiseasesEncephalomyelitisAutoantibodiesFemaleHumansMyelin-Oligodendrocyte GlycoproteinPlacentaPregnancyAutoantibodiesMyelin-Oligodendrocyte Glycoproteinencephalomyelitismyelin oligodendrocyte glycoprotein antibodypostpartumpregnancyrelapsetransplacental transport

Identifiers

PMID36070939
PMCPMC10125808
OpenAlexW4294879415

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.