Evidence map›Paper›PMID 36070938›Full record

ArticleInternal medicine (Tokyo, Japan)2023

Successful Discontinuation of Glucocorticoid Treatment after Administration of a Calcineurin Inhibitor for Nephrotic Syndrome in a Patient with Lupus Nephritis.

Masato Sawamura, Naoki Sawa, Daisuke Ikuma, Yuki Oba, Masayuki Yamanouchi, Akinari Sekine, Hiroki Mizuno, Eiko Hasegawa, Tatsuya Suwabe, Junichi Hoshino and 4 more

Abstract read
In one paragraph

Article in Internal medicine (Tokyo, Japan), 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

14 authors.

Masato SawamuraNephrology Center and Department of Rheumatology, Toranomon Hospital, Japan.
Naoki SawaNephrology Center and Department of Rheumatology, Toranomon Hospital, Japan.
Daisuke IkumaNephrology Center and Department of Rheumatology, Toranomon Hospital, Japan.
Yuki ObaNephrology Center and Department of Rheumatology, Toranomon Hospital, Japan.
Masayuki YamanouchiNephrology Center and Department of Rheumatology, Toranomon Hospital, Japan.
Akinari SekineNephrology Center and Department of Rheumatology, Toranomon Hospital, Japan.
Hiroki MizunoNephrology Center and Department of Rheumatology, Toranomon Hospital, Japan.
Eiko HasegawaNephrology Center and Department of Rheumatology, Toranomon Hospital, Japan.
Tatsuya SuwabeNephrology Center and Department of Rheumatology, Toranomon Hospital, Japan.
Junichi HoshinoNephrology Center and Department of Rheumatology, Toranomon Hospital, Japan.
Kei KonoDepartment of Pathology, Toranomon Hospital, Japan.
Keiichi KinowakiDepartment of Pathology, Toranomon Hospital, Japan.
Kenichi OhashiDepartment of Pathology, Toranomon Hospital, Japan.
Yoshifumi UbaraNephrology Center and Department of Rheumatology, Toranomon Hospital, Japan.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Systemic lupus erythematosus was diagnosed in a patient at 43 years old. When proteinuria recurred at 57 years old, the first kidney biopsy was performed, and class IV-G (A) +V lupus nephritis was diagnosed. The prednisolone dose was increased to 40 mg/day, and cyclosporine A was introduced. After 1 year, proteinuria had decreased to 0.1 g/day. Prednisolone was discontinued three years later, and cyclosporine A was continued. Thereafter, proteinuria did not reoccur. At 67 years old, a second kidney biopsy showed complete remission of lupus nephritis. Cyclosporine A enabled permanent discontinuation of glucocorticoids in a patient with lupus nephritis.

Indexed as

Lupus Erythematosus, SystemicLupus NephritisNephrotic SyndromeAdultAgedCalcineurin InhibitorsCyclosporineGlucocorticoidsHumansImmunosuppressive AgentsMiddle AgedPrednisoloneProteinuriaCalcineurin InhibitorsCyclosporineGlucocorticoidsImmunosuppressive AgentsPrednisolonecalcineurin inhibitorglucocorticoidlupus nephritissystemic lupus erythematosus

Identifiers

PMID36070938
PMCPMC10125829

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.