Evidence map›Paper›PMID 36070788›Full record

ReviewLancet (London, England)2022

Acute respiratory distress syndrome in adults: diagnosis, outcomes, long-term sequelae, and management.

Ellen A Gorman, Cecilia M O'Kane, Daniel F McAuley

2 registry-linked trialsAbstract readReview
PubMed Publisher
In one paragraph

Review in Lancet (London, England), 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to 2 registered trials, which are not on this map. Cited by 250 papers, 4 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
250citing papers in PubMed, 4 pooled it
51.5field-weighted citation impact, top 1% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT07328997 completednot on this mapstarted 2024, after this paper: background citation

Exploration of Diagnosis and Treatment Strategies and Prognostic Prediction Models for Acute Respiratory Distress Syndrome Based on Radiographic Evaluations Assessed by Artificial Intelligence

TypeobservationalSponsorShanghai Zhongshan HospitalRan2024 to 2025Enrolled400ConditionsARDS (Acute Respiratory Distress Syndrome), AI (Artificial Intelligence)ArmsCT scan
NCT07779642 phase2not yet recruitingnot on this mapstarted 2026, after this paper: background citation

Precision Medicine Adaptive Network Platform Trial in Hypoxemic Acute Respiratory Failure

TypeinterventionalSponsorUniversity of Colorado, DenverRan2026 to 2030Enrolled300ConditionsARDS (Acute Respiratory Distress Syndrome), Acute Hypoxic Respiratory FailureArmsSimvastatin, Baricitinib
3 · Its place in the literature

Who cites it

250 citing papers in PubMed, 4 syntheses or guidelines pooled it, 361 citations in OpenAlex.

  1. Joint statement on evidence-based practices in mechanical ventilation: suggestions from two Brazilian medical societies.Jornal brasileiro de pneumologia : publicacao oficial da Sociedade Brasileira de Pneumologia e Tisilogia · 2025
    Guideline
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190 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

3 authors at 1 institution in 1 country.

Ellen A GormanWellcome-Wolfson Institute for Experimental Medicine, Queen's University Belfast, Belfast, UK.
Cecilia M O'KaneWellcome-Wolfson Institute for Experimental Medicine, Queen's University Belfast, Belfast, UK.
Daniel F McAuleyWellcome-Wolfson Institute for Experimental Medicine, Queen's University Belfast, Belfast, UK. Electronic address: d.f.mcauley@qub.ac.uk.
Queen's University Belfast · GB

Funding

Wellcome Trust 106939/Z/15/Z
6 · The paper itself

Abstract

Acute respiratory distress syndrome (ARDS) is characterised by acute hypoxaemic respiratory failure with bilateral infiltrates on chest imaging, which is not fully explained by cardiac failure or fluid overload. ARDS is defined by the Berlin criteria. In this Series paper the diagnosis, management, outcomes, and long-term sequelae of ARDS are reviewed. Potential limitations of the ARDS definition and evidence that could inform future revisions are considered. Guideline recommendations, evidence, and uncertainties in relation to ARDS management are discussed. The future of ARDS strives towards a precision medicine approach, and the framework of treatable traits in ARDS diagnosis and management is explored.

Indexed as

Respiratory Distress SyndromeRespiratory InsufficiencyAdultDiagnostic ImagingHumansPhenotype

Identifiers

PMID36070788
OpenAlexW4294767945

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.