Evidence map›Paper›PMID 36070158›Full record

ArticleArchives of osteoporosis2022

Prevalent vertebral fractures among urban-dwelling Chinese postmenopausal women: a population-based, randomized-sampling, cross-sectional study.

Weibo Xia, Qiang Liu, Jinhan Lv, Zhenlin Zhang, Wen Wu, Zhongjian Xie, Jianting Chen, Liang He, Jian Dong, Zhenming Hu and 4 more

Abstract read
In one paragraph

Article in Archives of osteoporosis, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 14 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
14citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

14 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Pooled it
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  3. Machine learning-based screening model for osteoporosis in Chinese postmenopausal women: a nationwide study with prospective fracture validation.Osteoporosis international : a journal established as result of cooperation between the European Foundation for Osteoporosis and the National Osteoporosis Foundation of the USA · 2026
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  6. Beyond postmenopausal osteoporosis: reply to comments by Ömer Faruk Öz.Osteoporosis international : a journal established as result of cooperation between the European Foundation for Osteoporosis and the National Osteoporosis Foundation of the USA · 2026
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

14 authors.

Weibo Xia *Department of Endocrinology, Key Laboratory of Endocrinology, National Commission of Health, State Key Laboratory of Complex Severe and Rare Diseases, Peking Union Medical College Hospital, Chinese Academy of Medical Sciences, Beijing, China. xiaweibo8301@163.com.
Qiang Liu *Shanxi Dayi Hospital, Taiyuan, Shanxi, China. sxdyy001@163.com.
Jinhan Lv *The People's Hospital of Ningxia Hui Autonomous Region, Yinchuan, Ningxia, China.
Zhenlin ZhangDepartment of Osteoporosis and Bone Disease, The Sixth People's Hospital, Shanghai Jiaotong University, Shanghai, China.
Wen WuGuangdong Provincial People's Hospital, Guangzhou, Guangdong, China.
Zhongjian XieNational Clinical Research Center for Metabolic Diseases, Hunan Provincial Key Laboratory of Metabolic Bone Diseases, and Department of Metabolism and Endocrinology, The Second Xiangya Hospital, Central South University, 139 Middle Renmin Road, Changsha, Hunan, China.
Jianting ChenDivision of Spine Surgery, Department of Orthopaedics, Nanfang Hospital, Southern Medical University, Guangzhou, China.
Liang HeBeijing Jishuitan Hospital, Beijing, China.
Jian DongFudan University Zhongshan Hospital, Shanghai, China.
Zhenming HuThe First Affiliated Hospital of Chongqing Medical University, Chongqing, China.
Qiang LinDepartment of Radiology, Peking Union Medical College Hospital, Chinese Academy of Medical Science, Beijing, China.
Wei YuDepartment of Radiology, Peking Union Medical College Hospital, Chinese Academy of Medical Science, Beijing, China.
Fang WeiMedical Affairs & Outcomes Research, Organon China, Shanghai, China.
Jue WangGlobal Medical and Scientific Affairs, Merck Research Laboratories, MSD China, Shanghai, China.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

In this population-based, cross-sectional study, we investigated vertebral fracture (VF) prevalence among Chinese postmenopausal women. We found 14.7% of population had VFs, which increased with age. Age ≥ 65 years, hip fracture, and densitometric osteoporosis were significantly associated with VFs. The prevalence of osteoporosis was remarkably high. PURPOSE: To investigate VF prevalence among Chinese postmenopausal women in this population-based, randomized-sampling, cross-sectional study.

methodsThe investigator obtained lists of women from communities. Randomization was performed using SAS programming based on age group in each region. Postmenopausal women aged ≥ 50 years in the urban community were included. The investigator interviewed subjects to collect self-reported data and measured BMD. Spine radiographs were adjudicated by Genant's semi-quantitative method. VFs were defined as fractures of at least one vertebra classified by Genant's score 1-3 and were analyzed using descriptive statistics.

resultsA total of 31,205 women listed for randomized sampling from 10 Tier-3 hospitals at 5 regions. Of 2634 women in the full analysis set, 14.7% (388/2634, 95% CI: 13.4, 17.1) had prevalent VFs. VF prevalence increased with age (Cochran-Armitage test p < 0.0001) and was significantly higher in women aged ≥ 65. VF prevalence did not differ between North (14.4%, 95% CI: 12.5, 16.4) and South China (15.1%, 95% CI: 13.3, 17.1). In women with no prior VFs, prevalent VFs were 12.4% (95% CI: 11.2, 13.7). Age ≥ 65 years (OR: 2.57, 95% CI: 1.91, 3.48), hip fracture (OR: 2.28, 95% CI: 1.09, 4.76), and densitometric osteoporosis (OR: 2.52, 95% CI: 1.96, 3.22) were significantly associated with prevalent VFs. Prevalence of osteoporosis was 32.9% measured by BMD and 40.8% using NOF/IOF clinical diagnosis criteria.

conclusionVFs are prevalent among Chinese postmenopausal women who were ≥ 50 years and community-dwelled. Osteoporosis prevalence is remarkable when fragile fractures were part of clinical diagnosis.

Indexed as

Hip FracturesOsteoporosisOsteoporotic FracturesSpinal FracturesAgedBone DensityChinaCross-Sectional StudiesFemaleHumansPostmenopauseUrban PopulationCommunity-dwellingOsteoporosisPostmenopausal womenPrevalent vertebral fracturesRandomized sampling

Identifiers

PMID36070158
PMCPMC9452427

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.