Evidence map›Paper›PMID 36070146›Full record

ArticleSurgical endoscopy2023

Endoscopic submucosal dissection for tumors involving the ileocecal valve with extension into the terminal ileum: a multicenter study from the Hiroshima GI Endoscopy Research Group.

Hidenori Tanaka, Shiro Oka, Masaki Kunihiro, Shinji Nagata, Shosuke Kitamura, Toshio Kuwai, Yuko Hiraga, Akira Furudoi, Shinji Tanaka

Abstract readMulticenter Study
PubMed Publisher
In one paragraph

Article in Surgical endoscopy, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
0.6field-weighted citation impact, top 31% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed, 4 citations in OpenAlex.

  1. Saline-immersion technique for endoscopic submucosal dissection with traction for an ileocecal adenoma involving the ileal outlet.VideoGIE : an official video journal of the American Society for Gastrointestinal Endoscopy · 2026
    Article
  2. Endoscopic approach to large non-pedunculated colorectal polyps.Journal of the Canadian Association of Gastroenterology · 2025
    Article
  3. Article
  4. Article
  5. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 6 institutions in 1 country.

Hidenori TanakaDepartment of Endoscopy, Hiroshima University Hospital, Hiroshima, Japan.
Shiro OkaDepartment of Gastroenterology and Metabolism, Hiroshima University Hospital, 1-2-3, Kasumi, Minamiku, Hiroshima, 734-8551, Japan. oka4683@hiroshima-u.ac.jp.ORCID http://orcid.org/0000-0002-1773-8293
Masaki KunihiroDepartment of Internal Medicine, Hiroshima City Hiroshima Citizens Hospital, Hiroshima, Japan.
Shinji NagataDepartment of Gastroenterology, Hiroshima City Asa Citizens Hospital, Hiroshima, Japan.
Shosuke KitamuraDepartment of Gastroenterology, JA Onomichi General Hospital, Onomichi, Japan.
Toshio KuwaiDepartment of Gastroenterology, National Hospital Organization Kure Medical Center, Chugoku Cancer Center, Kure, Japan.
Yuko HiragaDepartment of Endoscopy, Hiroshima Prefectural Hospital, Hiroshima, Japan.
Akira FurudoiDepartment of Gastroenterology, JA Hiroshima General Hospital, Hatsukaichi, Japan.
Shinji TanakaDepartment of Endoscopy, Hiroshima University Hospital, Hiroshima, Japan.
Hiroshima University Hospital · JPHiroshima City Asa Citizens Hospital · JPHiroshima General Hospital · JPHiroshima Prefectural Hospital · JPNational Hospital Organization · JPOnomichi General Hospital · JP

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundThe efficacy and safety of endoscopic submucosal dissection (ESD) for tumors extending into the terminal ileum remain obscure. We aimed to evaluate the outcomes of ESD for tumors involving the ileocecal valve (ICV) with extension into the terminal ileum.

methodsSixty-eight patients (40 men; mean age, 67 years) with 68 tumors involving the ICV that were resected by ESD between December 2013 and December 2018 were included and classified into Group A (21 tumors with extension into the terminal ileum) and Group B (47 tumors without extension). ESD outcomes were compared between groups.

resultsThe clinical features of the patients and tumors were not significantly different between the groups. There were no significant differences in en bloc resection rate (95% and 94%, respectively; p = 0.79), R0 resection rate (90% and 89%, respectively; p = 0.89), procedure time (95 ± 54 min and 94 ± 69 min, respectively; p = 0.64), postoperative bleeding rate (5% and 3%, respectively; p = 0.79), intraoperative perforation rate (0% and 4%, respectively; p = 0.34), delayed perforation rate (0% and 0%, respectively), or postoperative symptomatic stenosis rate (0% and 0%, respectively) between Groups A and B. No specific factors related to the outcomes of ESD were found by subgroup analysis according to the dominance and degree of circumference of the ICV. Local recurrence was observed in 1 patient in Group A who was retreated using ESD.

conclusionsESD for tumors involving the ICV with extension into the terminal ileum is safe and effective.

Indexed as

Colorectal NeoplasmsEndoscopic Mucosal ResectionIleocecal ValveAgedDissectionEndoscopy, GastrointestinalHumansIleumIntestinal MucosaMalePostoperative ComplicationsRetrospective StudiesTreatment OutcomeColorectal endoscopic submucosal dissectionEndoscopyIleocecal valveStenosisTerminal ileum

Identifiers

PMID36070146
OpenAlexW4294917825

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.