Evidence map›Paper›PMID 36069954›Full record

ArticleJournal of experimental orthopaedics2022

Articular cartilage delamination at eight years following cellular-based repair procedures: a case reports.

Alberto Gobbi, John G Lane, Macarena Morales, Riccardo D'Ambrosi

Abstract read
In one paragraph

Article in Journal of experimental orthopaedics, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed.

  1. Article
  2. Review
  3. Shaping experimental orthopaedics.Journal of experimental orthopaedics · 2023
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Alberto GobbiO.A.S.I. Bioresearch Foundation Gobbi Onlus, Milan, Italy.
John G LaneDepartment of Orthopaedic Surgery, University of California, San Diego, San Diego, CA, USA.
Macarena MoralesO.A.S.I. Bioresearch Foundation Gobbi Onlus, Milan, Italy.
Riccardo D'AmbrosiIRCCS Istituto Ortopedico Galeazzi, Milan, Italy. riccardo.dambrosi@hotmail.it.ORCID http://orcid.org/0000-0002-1216-792X

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

This report describes two cases of late cartilage delamination in two young adults after two different autologous cell-based techniques for cartilage restoration: 1. Matrix-assisted autologous chondrocyte implantation (MACI) and 2. Hyaluronic acid-bone marrow aspirate concentrate (HA-BMAC). Both cases demonstrate that even in patients who do not present with any ongoing symptoms after primary surgery, a cellular-based graft's subsequent delamination can occur later. It is possible that regardless of the technique used or the time passed since the surgery, a graft failure may occur at some level, causing delamination of a previously asymptomatic cartilage restoration graft and a traumatic event with long-term follow-up. Surgeons must be alert to this injury and describe histologic findings to determine where failure occurs.

Identifiers

PMID36069954
PMCPMC9452617

What OpenQuestion holds

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LicenceCC BY
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.